Previous evidence, including published National Lung Cancer Screening Trial (NLST) results, shows that computed tomography (CT) lung cancer screening significantly reduces lung cancer deaths in high risk patients*, and is appropriate, with careful patient selection and follow-up. This benefit significantly outweighs the comparatively modest rate of overdiagnosis noted in an article published online Dec. 9 in JAMA Internal Medicine. The American College of Radiology (ACR) will continue guideline and appropriateness criteria creation to support CT lung cancer screening programs across the country.