August 7, 2019 — Synaptive Medical announced the U.S. launch and availability of Modus Plan featuring BrightMatter AutoSeg. This release provides the additional capability of automated tractography segmentation into patient-specific bundles of interest. Modus Plan, previously referred to as BrightMatter Plan, will supplement Synaptive’s fully integrated suite of surgical technologies, including its robotically controlled microscope, Modus V.
Historically, it has taken significant time for surgeons to manually generate tractography, which has been one of the limitations to widespread adoption of this useful patient-specific information. Each patient’s neuroanatomy consists of unique patterns of white matter that indicate key areas of the brain that control function. Synaptive’s Modus Plan software automatically generates dynamic whole-brain tractography. This new capability takes it one step further by visually segmenting these tracts into patient-specific bundles, thereby providing surgeons valuable information about areas of the brain during surgical procedures.
Synaptive developed Modus Plan and its BrightMatter AutoSeg feature with neurosurgeons in mind. Image-guided technology is a critical component of modern neurosurgical practice, especially when dealing with deep-seated lesions, as standard anatomical approaches may not take into account critical white matter tracts. Automatically segmented tractography can be imported into image-guided systems, including both Synaptive’s BrightMatter Guide and third-party systems. With this preoperative and intraoperative use, automated segmentation is foundational to surgical planning, decision-making during surgery and ultimately improving patient outcomes.
The tractography segmentation feature is intended to be incorporated into hospital systems — subject to regulatory clearances — across multiple markets already using Synaptive’s fully integrated suite of neurological solutions.
For more information: www.synaptivemedical.com
November 20, 2025 
