News | Women's Health | April 12, 2017

Study Finds Breast Cancer Rates Increasing Among Asian Americans

Researchers examined breast cancer incidence rates among seven Asian American ethnic groups in California

Study Finds Breast Cancer Rates Increasing Among Asian Americans

April 12, 2017 — In contrast to other U.S. racial/ethnic groups, Asian Americans have experienced steadily increasing breast cancer rates over the past 15 years.

To better understand potential contributors to this increase, researchers at the Cancer Prevention Institute of California (CPIC) examined cancer incidence trends by age and stage among women from seven Asian American ethnic groups in California from 1988 through 2013. The findings were epublished ahead of print in the April issue of Breast Cancer Research and Treatment.

Although prior research has examined subtype-specific incidence patterns among Asians/Pacific Islanders as whole, this is the first examination of subtype-specific incidence patterns among Asian American ethnicities and the variation among Asian American ethnic groups. 

Asian Americans includes populations from nearly 30 countries with differing migration patterns, socioeconomic status, health behaviors and culture, all which contribute to differences in disease incidence. In this study, seven major ethnicities were evaluated:

  • Chinese;
  • Japanese;
  • Korean;
  • Filipino;
  • Vietnamese;
  • South Asians (Asian Indians and Pakistanis); and
  • Southeast Asians (Cambodians, Laotians, Hmong, Thai).

All Asian Americans groups, with the exception of Japanese, experienced an overall incidence increase. The largest increase was observed among Koreans, South Asians and Southeast Asians. Rates increased for distant stage disease among Filipinas.

Among women over age 50, increases occurred in all Asian American ethnic groups while for women younger than 50 large increases occurred for Vietnamese and other Southeast Asian groups. Although breast cancer incidence rates in Asian American women as a whole were lower than rates for whites, the rates for Japanese and Filipinas under age 50 were comparable to rates for similarly aged white women.

Breast cancer incidence also varies by disease subtype defined by tumor expression of hormone receptors and human epidermal growth factor receptor 2 (HER2). Within California, proportionally more breast cancers expressed HER2 in Korean, Filipino, Vietnamese and Chinese women than in white women.

According to Scarlett Lin Gomez, the lead researcher of the study, “These patterns warrant additional attention to public health prioritization to target disparities in access to care, as well as further research in identifying relevant breast cancer risk factors for specific breast cancer subtypes. In particular, studies should investigate risk factors, perhaps early-life exposures, underlying the higher rates of breast cancer among young Filipino and Japanese women, with attention to possible genetic susceptibility.”

Increasing trends of late-stage disease, particularly among Filipino, Korean and South Asian women, suggest a need for higher rates of mammography screening in these populations. Mammography utilization rates in California are slightly lower in Asian American women than in other racial/ethnic groups; among Asian Americans, Korean and South Asian women have the lowest mammography utilization, consistent with their higher rates of later-stage disease.

The disproportionately high rates of some HER2 negative overexpressing subtypes also require better understanding, as this subtype tends to grow more quickly, spread more aggressively, and present more often as high-grade disease than the more common hormone receptors or HER2 negative tumors.

To conduct this study, researchers used data from the population-based California Cancer Registry in a state that is both the largest in the U.S. and has the most substantial population of Asian Americans. Comparison data were drawn for whites. From 1988-2013, researchers identified 45,721 invasive breast cancer cases among Asian Americans.

Other researchers who participated in this study from CPIC are Julie Von Behren, Meg McKinley, Christina A. Clarke, Salma Shariff-Marco, Iona Cheng, Peggy Reynolds and Sally L. Glaser.

This work was supported by the Stanford Cancer Institute and the National Cancer Institute’s Surveillance, Epidemiology and End Results Program under contract HHSN261201000140C awarded to the Cancer Prevention Institute of California.

For more information: www.springer.com

Related Content

New Data Demonstrates Safety Profile of GammaTile Therapy for Various Brain Tumors
News | Brachytherapy Systems | June 18, 2019
GT Medical Technologies Inc. announced the presentation of clinical data from a prospective study of GammaTile Therapy...
Black Men Less Likely to Adopt Active Surveillance for Low-Risk Prostate Cancer
News | Prostate Cancer | June 17, 2019
A new study reveals black men are less likely than white men to adopt an active surveillance strategy for their...
Warm Springs Health & Wellness Center Implements Digisonics Solution for OB Ultrasound
News | Ultrasound Women's Health | June 17, 2019
Warm Springs Health & Wellness Center in Warm Springs, Ore., has selected the Digisonics OB PACS (picture archiving...
Fujifilm Announces Nationwide Breast Health Campaign With Mobile Mammography Coach

At the center of the campaign, Fujifilm will be traveling around the U.S. with its "Aspire to Be Fearless" mobile mammography coach to provide educational opportunities for clinicians, raise awareness about the importance of screening and will be providing mammograms to the underserved population in key locations.

News | Mammography | June 14, 2019
Fujifilm Medical Systems U.S.A. Inc. announced a nationwide awareness campaign titled ‘Aspire to Be Fearless’ focused...
Ikonopedia Showcases Risk Assessment and Resolution Manager Tools at SIIM and AHRA
News | Mammography Reporting Software | June 13, 2019
Ikonopedia will showcase its suite of structured breast reporting and Mammography Quality Standards Act (MQSA)...
Sponsored Content | Videos | Radiology Imaging | June 13, 2019
In an interview with itnTV, Henry Izawa, vice president, modality solutions and clinical affairs, Fujifilm Medical Sy
iCAD Introduces ProFound AI for 2D Mammography in Europe
News | Artificial Intelligence | June 13, 2019
iCAD Inc. announced the launch of ProFound AI for 2D Mammography in Europe. This software is the latest addition to...
Three Palm Software Releases WorkstationOne Version 1.8.8
Technology | Mammography Reporting Software | June 12, 2019
Three Palm Software announced the release of the 1.8.8 version of its breast imaging workstation, WorkstationOne. This...
Volpara Health Technologies to Acquire MRS Systems Inc.
News | Mammography Reporting Software | June 04, 2019
Volpara Health Technologies, Volpara Solutions' parent company, has signed a binding agreement to acquire U.S.-based...
AI Biomarker Demonstrates High Predictive Power for Lung Cancer Immunotherapy
News | Artificial Intelligence | May 31, 2019
Lunit announced an abstract presentation of its artificial intelligence (AI) precision medicine research portfolio at...