News | May 27, 2009

Stereotactic Body Radiation Therapy Helps Manage Lung Cancer

May 28, 2009 - Stereotactic body radiotherapy (SBRT) when used to treat certain patients with non-small-cell lung cancer provided a 3-year local tumor control rate of 90 percent or higher with minor toxicity, reported Scandinavian researchers report in a May 4th online edition of the Journal of Clinical Oncology.

Lead investigator, Pia Baumann, a medical doctor at Karolinska University Hospital Solna, Stockholm, and colleagues conducted a phase II trial that included 40 patients with stage 1 tumors and 17 with stage 2 tumors who underwent SBRT every second day for a median of 5 days of treatment.

At 1 year, overall survival was 88 percent and cancer-specific survival was 93%. At 3 years, progression-free survival was 52%, overall survival was 60% and cancer-specific survival was 88%. There was no significant survival difference between patients with T1 and T2 tumors.

At a median follow-up of 35 months, 7 patients had died from lung cancer and 20 from concurrent disease. Estimated local control at 3 years was 92%. The estimated risk of failure due to local, regional or distant metastases was significantly greater in patients with T2 tumors than in those with T1 tumors (41% versus 18%).

The researchers suggest that based on these findings, SBRT "may even challenge surgery in operable instances."

SBRT is efficient in eradicating tumors with only limited side effects in patients with medically inoperable stage I non-small cell lung cancer, indicated Dr. Baumann. "SBRT is also useful for treating metastatic tumors in diverse organs."

Source: J Clin Oncol 2009;27.

For more information:

Related Content

SpaceOAR Hydrogel Now Available in Japan
News | Patient Positioning Radiation Therapy | July 16, 2018
Augmenix K.K. announced that SpaceOAR hydrogel, a soft, implanted absorbable gel spacer is now available to all...
RaySearch Releases New Version of RayCare OIS
Technology | Oncology Information Management Systems (OIMS) | July 13, 2018
RaySearch has released RayCare 2A, the latest version of its flagship oncology information system (OIS). RayCare is...
Lack of Insurance Coverage Delaying Proton Therapy Clinical Trials
News | Proton Therapy | July 12, 2018
Randomized clinical trials are the gold standard of cancer research and can shed light on whether innovative, new...
Bruce Power Joins Forces With ITM to Supply Lutetium-177 for Cancer Therapy
News | Radiation Therapy | July 11, 2018
Canadian nuclear power company Bruce Power and German-based Isotope Technologies Garching (ITG) signed an agreement to...
MedStar Georgetown University Hospital Now Clinical With RayStation and Hyperscan
News | Treatment Planning | July 05, 2018
MedStar Georgetown University Hospital in Washington D.C., has begun patient treatments using the RayStation treatment...
Northern Centre for Cancer Care (NCCC)

Northern Centre for Cancer Care (NCCC).

Sponsored Content | Case Study | Radiation Therapy | July 05, 2018
Established in 2009, Northern Centre for Cancer Care (NCCC) is the largest center of its kind in the north of England....
Researcher Investigates Eliminating Radiation for HER2-Positive Breast Cancer
News | Radiation Therapy | July 02, 2018
Researchers at The University of Kansas Cancer Center have launched a clinical trial that eliminates radiation from the...
New Prostate Cancer Radiotherapy Technique Aims to Preserve Sexual Function
News | Radiation Therapy | June 18, 2018
A multicenter clinical trial being led by UT Southwestern physicians is testing a technique for sparing nerve bundles...
Elekta Unity High-Field MR-Linac Receives CE Mark
News | Image Guided Radiation Therapy (IGRT) | June 18, 2018
Elekta announced that its Elekta Unity magnetic resonance radiation therapy (MR/RT) system has received CE mark,...
Washington University in St. Louis Begins Clinical Treatments With ViewRay MRIdian Linac
News | Image Guided Radiation Therapy (IGRT) | June 14, 2018
June 14, 2018 — The Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in S
Overlay Init