News | May 11, 2010

SRS Safe, Effective for Children with Arteriovenous Malformations

May 11, 2010 - Stereotactic radiosurgery using gamma knife is a safe and effective option for selected children with arteriovenous malformations, according to a recent study presented at the American Association of Neurological Surgeons Annual Meeting in Philadelphia last week.

An intracranial arteriovenous malformation is an abnormal tangle of blood vessels in the brain. In an arteriovenous malformation, the blood passes directly from arteries to veins via the abnormal vessels, and the brain is not allowed to absorb oxygen from the blood, which can result in stroke-like symptoms, seizures or other symptoms. Arteriovenous malformations appear to be congenital. About 0.14 percent of the population has an arteriovenous malformation.

The gamma knife is a radiosurgical treatment that delivers a dose of gamma radiation to the target with surgical precision. It is also the most accepted and widely used radiosurgery treatment in the world.

"Using stereotactic radiosurgery, focused radiation is directed to the arteriovenous malformation causing the vessels to slowly block off over several years and the majority of patients are protected from the risk of intracranial bleeding," said Bruce Pollock, M.D., a Mayo Clinic neurosurgeon and the author of the study.

Pollock and a team of Mayo Clinic researchers collected data from 48 patients, ages 18 or under, who had Gamma Knife stereotactic radiosurgery for an arteriovenous malformation between 1990 and 2007 and had more than 12 months of follow-up data. Twenty-seven patients (57 percent) had a previous brain hemorrhage, and 15 of the arteriovenous malformations were in deep locations. The team found that 52 percent (25 patients) had obliteration of the malformation after their initial radiosurgery. Repeat radiosurgery was performed in 12 patients, five of whom had obliteration, for a total obliteration rate of 63 percent. Three patients had radiation-related deficits after initial or repeat radiosurgery, but no patients had arteriovenous malformation bleeding, neuro-cognitive decline or radiation-induced tumor after radiosurgery.

"We believe that Gamma Knife stereotactic radiosurgery is a safe treatment option for many children with arteriovenous malformations," said Pollack.

For more information: www.mayoclinic.orgstereotactic-radiosurgery/gamma-knife.html and www.aans.org

Related Content

First Patient Treated in Online Adaptive Radiotherapy Trial With CyberKnife System
News | Stereotactic Body Radiation Therapy (SBRT) | April 06, 2018
Accuray Inc. and Erasmus MC announced the first patient has been successfully treated using an online-adaptive (OA)...
​ITN Celebrates World Cancer Day 2018
News | Radiation Oncology | February 01, 2018
World Cancer Day takes place annually on Feb.
Age Impacts Post-treatment Mortality for Early-stage Lung Cancer Patients

Image courtesy of Henri Becquerel Cancer Center

News | Stereotactic Body Radiation Therapy (SBRT) | January 24, 2018
A University of Colorado Cancer Center study published in the Journal of Clinical Oncology explores mortality in the...
FDA Clears GammaPod Stereotactic Radiotherapy System for Breast Cancer Treatment
Technology | Stereotactic Body Radiation Therapy (SBRT) | December 22, 2017
The U.S. Food and Drug Administration (FDA) has cleared the new GammaPod noninvasive stereotactic radiotherapy system...
Elekta and Brainlab Offer Streamlined Workflow for Stereotactic Radiotherapy
News | Radiation Therapy | October 16, 2017
Elekta and Brainlab have reconfirmed their alliance for the integrated use of the Elekta Versa HD linear accelerator...
Pancreatic Cancer Outcome Highlights via On-table Adaptive MR-guided Radiation Therapy, MRI guided RT.
Sponsored Content | Webinar | Radiation Therapy | October 13, 2017
The webinar "Pancreatic Cancer Outcome Highlights via On-table Adaptive MR-guided Radiation" was presented by Parag P
CyberKnife System Provides Excellent Long-Term Control of Low-Risk Prostate Cancer
News | Stereotactic Body Radiation Therapy (SBRT) | October 10, 2017
Accuray Inc. announced that data from a prospective study of 230 men with low-risk prostate cancer showed 98.4 percent...
Adding Radiation to Chemotherapy May Dramatically Improve Survival for Advanced-Stage NSCLC Patients
News | Stereotactic Body Radiation Therapy (SBRT) | September 26, 2017
Combining radiation therapy with chemotherapy for patients with limited metastatic non-small cell lung cancer (NSCLC)...
more healthcare providers and patients are choosing options such as Gamma Knife stereotactic radiosurgery
News | Radiation Therapy | July 31, 2017
Each year, up to 650,000 people who were previously diagnosed with various forms of cancer will develop brain...
Surgery and High-Dose SBRT Radiation Can Be Combined to Treat Kidney Cancer
News | Stereotactic Body Radiation Therapy (SBRT) | July 05, 2017
A new study from Roswell Park Cancer Institute reporting the findings of the first clinical trial to evaluate the...
Overlay Init