News | May 09, 2011

SAVI Research Project: Initial Findings Reported at ABS

May 9, 2011 - Initial findings from the SAVI Collaborative Research Project (SCRP), on SAVI radiation therapy for breast cancer, were presented at the recent annual meeting of the American Brachytherapy Society (ABS).

The SAVI Collaborative Research Project was established to produce additional research, presentations, and peer-reviewed, published literature on SAVI. The data collected thus far represents the largest subset of patients who have received accelerated partial breast irradiation (APBI) with the SAVI applicator. The SAVI applicator is made by Cianna Medical.

The registry is lead by Catheryn Yashar, M.D., of the University of California San Diego School of Medicine, and Robert R. Kuske, M.D., a pioneer in APBI and medical director at Arizona Breast Cancer Specialists.

"The SAVI registry is adding important scientific knowledge to the field of APBI," said Yashar, who presented the initial data in a podium presentation at ABS. "Because there are several forms of APBI, this research allows us to compare the various forms and better determine which devices are suited to particular types of patients."

The findings presented at ABS are the first to be reported from the SCRP. Based on a retrospective review of 294 patients treated at five clinical sites, researchers concluded the overall dosimetry of SAVI was excellent and that the data demonstrate SAVI's unique ability to sculpt the radiation dose away from the skin and ribs while selectively treating targeted tissue.

The SAVI multi-catheter applicator is available in four sizes designed to fit different surgical cavity sizes. The research presented at ABS showed that the two sizes used to treat larger cavities provide dosimetric coverage that is comparable to published data for various forms of "balloon" breast brachytherapy devices. The two sizes for women with smaller breasts and cavities were found to be useful in cases where anatomical restrictions might preclude use of a balloon device.

SAVI delivers accelerated partial breast irradiation APBI as part of breast conservation therapy (BCT). By specifically targeting radiation where the cancer is most likely to recur, SAVI reduces treatment time from six weeks with traditional whole-breast irradiation, to just five days.

The SAVI device allows physicians to customize radiation dose based on patient-specific anatomy, and is the ideal single-entry breast brachytherapy treatment method when the skin and ribs are close to the lumpectomy cavity. This unique ability can make the benefits of APBI available to twice as many women, as well as result in better outcomes including less skin toxicity, reduced risk of infection and improved cosmesis.

"Breast conservation therapy is now preferred over mastectomy for early stage breast cancer because the survival rates are the same and BCT allows the woman to preserve her breast and sense of wholeness," said Dr. Kuske. "For many women with busy lives, a six to seven week course of radiation is prohibitive, so a five-day alternative is very attractive. Women are also drawn to APBI because it minimizes radiation exposure to other parts of the body. In the evolution of this shorter, more targeted treatment option, the SCRP study demonstrates that size and anatomy no longer need to restrict eligibility for APBI. For many of my patients, SAVI has been my treatment of choice."

For more information: www.ciannamedical.com

Related Content

Insightec Announces Expanded Reach of MR-Guided Focused Ultrasound
News | Focused Ultrasound Therapy | August 22, 2017
Insightec announced recently that worldwide adoption of magnetic resonance (MR)-guided focused ultrasound continues to...
UCLA Study Offers Roadmap to Personalized Therapies for Sarcoma
News | Oncology Diagnostics | August 22, 2017
A new UCLA study is the first to identify patient and tumor characteristics that predict the successful creation of...
Sponsored Content | Videos | Information Technology | August 22, 2017
Melissa Martin, MS, president of the American Association of Physicists in Medicine (AAPM), discusses her vision of t
Comparison of Screening Recommendations Supports Annual Mammography
News | Mammography | August 22, 2017
When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue...
Sponsored Content | Videos | Proton Therapy | August 21, 2017
Mark Pankuch, Ph.D., director of medical physics at the Northwestern Medicine Chicago Proton Center, discusses the cl
Summit Cancer Center-Boise Treats First Cancer Patients With Accuray Radixact System
News | Image Guided Radiation Therapy (IGRT) | August 21, 2017
Accuray Inc. and the Summit Cancer Center-Boise announced that the center is now treating patients with the Radixact...
MedStar Georgetown Proton Center Selects RayStation for Treatment Planning
News | Treatment Planning | August 17, 2017
August 17, 2017 — The proton center at MedStar Georgetown University Hospital will utilize RayStation for planning on
DOSIsoft Releases ISOgray Proton Therapy Treatment Planning System
Technology | Treatment Planning | August 15, 2017
DOSIsoft SA announced the official release, with CE marking, of ISOgray Treatment Planning System (TPS) release 4.3 for...
First Radixact Results Presented at AAPM 2017
News | Radiation Therapy | August 10, 2017
Accuray Inc. announced that the first studies validating the benefits of the Radixact System were presented at the 59th...
MRI Reveals Striking Brain Differences in People with Genetic Autism

Example images for a control participant , a deletion carrier, and a duplication carrier. In the sagittal image of the deletion carrier, the thick corpus callosum, dens and craniocervical abnormality, and cerebellar ectopia are shown. For the duplication carrier, the sagittal image shows the thin corpus callosum and the axial image shows the increased ventricle size and decreased white matter volume. Image courtesy of the Radiological Society of North America (RSNA).

News | Neuro Imaging | August 09, 2017
August 9, 2017 — In the first major study of its kind, researchers using magnetic...
Overlay Init