News | July 20, 2008

RT for Rare Breast Cancer May Lower Recurrence Rate

July 20, 2008 - Patients with a rare type of breast cancer may benefit from receiving radiation therapy in addition to surgery to prevent recurrence, according to a study in the July issue of the International Journal of Radiation Oncology Biology Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

Phyllodes tumors are rare breast tumors that develop in the connective tissue of the breast, as opposed to more common carcinomas, which develop in the ducts or lobules of the breast. Most patients are treated for phyllodes tumors with either a lumpectomy or mastectomy, with only a small fraction of patients receiving radiation therapy.

Traditionally, adjuvant radiation therapy is recommended for cancer patients with local recurrence risks of 15 percent or greater, but the value of adjuvant radiation therapy has not been extensively studied for phyllodes tumors because they are so rare.

Researchers at the Division of Radiation Oncology, Department of Medical Physics, and Department of General and Oncologic Surgery at City of Hope National Medical Center in Duarte, CA, sought to determine the local recurrence rates of phyllodes tumors based on tumor size and the type of surgery performed and whether adjuvant radiation therapy should be considered as a treatment for some phyllodes tumor patients to reduce their local recurrence rate.

“Typically these tumors are treated well by surgery alone. However, local recurrences are not uncommon,” said Richard Pezner, M.D., lead author of the study and a radiation oncologist at City of Hope National Medical Center.

The study authors reviewed records of 478 patients with malignant phyllodes tumors who were treated between March 1964 and August 2005. The records came from the IMPAC National Oncology Database, which consists of tumor registries from 130 hospitals.

The researchers found that the risk of local recurrence for phyllodes tumors was related to tumor size and the type of surgery received. They determined that adjuvant radiation therapy should be evaluated for phyllodes tumor patients who received lumpectomies for tumors at least 2 centimeters in size or a mastectomy for tumors at least 10 centimeters in size to reduce the risk of recurrence.

Source: ASTRO (American Society for Therapeutic Radiology & Oncology)

For more information: www.astro.org

Related Content

Insightec Announces Expanded Reach of MR-Guided Focused Ultrasound
News | Focused Ultrasound Therapy | August 22, 2017
Insightec announced recently that worldwide adoption of magnetic resonance (MR)-guided focused ultrasound continues to...
UCLA Study Offers Roadmap to Personalized Therapies for Sarcoma
News | Oncology Diagnostics | August 22, 2017
A new UCLA study is the first to identify patient and tumor characteristics that predict the successful creation of...
Sponsored Content | Videos | Information Technology | August 22, 2017
Melissa Martin, MS, president of the American Association of Physicists in Medicine (AAPM), discusses her vision of t
Sponsored Content | Videos | Proton Therapy | August 21, 2017
Mark Pankuch, Ph.D., director of medical physics at the Northwestern Medicine Chicago Proton Center, discusses the cl
Summit Cancer Center-Boise Treats First Cancer Patients With Accuray Radixact System
News | Image Guided Radiation Therapy (IGRT) | August 21, 2017
Accuray Inc. and the Summit Cancer Center-Boise announced that the center is now treating patients with the Radixact...
MedStar Georgetown Proton Center Selects RayStation for Treatment Planning
News | Treatment Planning | August 17, 2017
August 17, 2017 — The proton center at MedStar Georgetown University Hospital will utilize RayStation for planning on
DOSIsoft Releases ISOgray Proton Therapy Treatment Planning System
Technology | Treatment Planning | August 15, 2017
DOSIsoft SA announced the official release, with CE marking, of ISOgray Treatment Planning System (TPS) release 4.3 for...
First Radixact Results Presented at AAPM 2017
News | Radiation Therapy | August 10, 2017
Accuray Inc. announced that the first studies validating the benefits of the Radixact System were presented at the 59th...
Clinical Data Supports Use of Xoft System for Endometrial Cancer
News | Brachytherapy Systems | August 03, 2017
Researchers presented clinical data supporting use of the Xoft Axxent Electronic Brachytherapy (eBx) System for the...
Overlay Init