News | July 13, 2009

Molecule Programmed to Act as Prostate Cancer "Homing Device"

July 13, 2009 - Purdue University researchers have developed a "homing device" for prostate cancer using by synthesizing a molecule that finds and penetrates prostate cancer cells and using imaging agents and therapeutic drugs that can link to the molecule and be carried with it as cargo.

In the study, led by Philip Low, professor of Biochemistry, Purdue University, radioimaging application for body scans and an optical imaging application used to measure prostate cancer cells in blood samples to detect prostate cancer.

The molecule the team created attaches to prostate-specific membrane antigen, or PSMA, a protein that is found on the membrane of more than 90 percent of all prostate cancers. It also is found on the blood vessels of most solid tumors and could provide a way to cut off the tumor blood supply. There may also be an indication for targeting molecule to be used to attack the vasculature of solid tumors of other types of cancers.

Two papers detailing the work of the Purdue team were published in the June 1 issue of Molecular Pharmaceutics. Endocyte Inc. funded the work.

For more information: www.acs.org

Related Content

Ensuring that the FMDS for MRI safety is mounted outside Zone IV provides maximum early warning.

Ensuring that the FMDS for MRI safety is mounted outside Zone IV provides maximum early warning. (Images courtesy of Metrasens)

Feature | Magnetic Resonance Imaging (MRI) | July 03, 2018 | By Tobias Gilk
Nearly every job in the country is subject to certain health and safety regulations. Construction workers must wear...
Carestream DRX-Revolution Nano Mobile X-ray System

The Carestream DRX-Revolution Nano Mobile X-ray System.

Feature | Digital Radiography (DR) | July 03, 2018 | By Melinda Taschetta-Millane
The mobile digital radiography (DR) segment is the largest segment by product type in the global digital mobile DR...
Feature | Proton Therapy | July 03, 2018 | By Jeff Zagoudis
The Alliance for Proton Therapy Access (APTA) released a national report in late May revealing the heavy emotional and...
New U.S. Tariffs on Chinese Goods Include Imaging Equipment
News | Radiology Business | June 15, 2018 | Jeff Zagoudis, Associate Editor
The Office of the U.S. Trade Representative (USTR) released the much-anticipated list of Chinese-manufactured goods...
Raysearch RayStation
Feature | Radiation Therapy | June 05, 2018 | By Melinda Taschetta-Millane
Treatment planning systems are at the heart of r...
Lung Decision Precision
News | Lung Cancer | June 04, 2018
For smokers and former smokers, the threat of lung cancer always lurks in the shadows.
Geraldine McGinty Elected First Female Chair of American College of Radiology

Image courtesy of the American College of Radiology

News | Radiology Business | May 22, 2018
The American College of Radiology (ACR) Board of Chancellors has elected Geraldine McGinty, M.D., MBA, FACR, as chair....
Joint ACR-SIIM Summit to Examine Economics of AI in Healthcare
News | Artificial Intelligence | May 15, 2018
On May 30, 2018, the American College of Radiology (ACR) Data Science Institute (DSI) and the Society for Imaging...
Metal artifact reduction led to a 20 percent increase in the planning target volume (PTV) in this prostate cancer case from Henry Ford Health System. The volume of the healthy bladder tissue to be spared was also reduced by 4 percent.

Metal artifact reduction led to a 20 percent increase in the planning target volume (PTV) in this prostate cancer case from Henry Ford Health System. The volume of the healthy bladder tissue to be spared was also reduced by 4 percent.

Feature | Computed Tomography (CT) | May 03, 2018 | By Jeff Zagoudis
Computed tomography (CT) has long been the standard of care for imaging to plan radiation therapy (RT) treatments. 
Charles E. Kahn Jr., M.D., M.S., will become editor of the new online journal, Radiology: Artificial Intelligence

Charles E. Kahn Jr., M.D., M.S.

News | Artificial Intelligence | May 02, 2018
The Board of Directors of the Radiological Society of North America (RSNA) announced that Charles E. Kahn Jr., M.D., M....
Overlay Init