News | May 20, 2015

Mirada Medical Highlights Deformable Image Registration at ESTRO 2015

Pair of studies examine role of advanced technique in radiotherapy planning

May 20, 2015 — State-of-the-art deformable image registration and multimodality imaging techniques continue to drive advances in radiation therapy clinical practice. Novel research into the utility and benefit of such advanced techniques are the topics that the Mirada Medical scientific team and collaborators presented at the 3rd ESTRO (European Society for Radiotherapy and Oncology) forum conference, April 24-28 in Barcelona, Spain.

The first study, entitled “The potential role of diagnostic position MRI with deformable registration for radiotherapy planning of HNSCC”, was in collaboration with Leeds St. James Hospital (U.K.). This study examined the use of magnetic resonance imaging (MRI) acquired in diagnostic position that are fused to the planning computed tomography (CT) using Mirada CT-MR Deformable Image Registration, and the consequent effects on contouring accuracy and intra-observer variability. Accurate target and organs-at-risk structures are a prerequisite for effective radiation treatment. The study compared a number of planning structures in head and neck squamous cell carcinoma patients drawn on the planning CT alone, diagnostic MRI alone and planning MRI alone. The results showed that the gross tumour volume (GTV) accuracy improved markedly when using the diagnostic MRI, and intra-observer variability reduced.

The second study, entitled “Fractionation-corrected doses with deformable registration as a tool for treatment plan comparison”, was in collaboration with Tampere University Hospital (Finland). It examines the role of Mirada CT-CT Deformable Image Registration in the task of decision-making for patients with recurrent disease. The study presents a framework for evaluating the dose to organs-at-risk when considering multiple treatments and compares the results when performing raw dose summation and biological dose summation — both with and without healing. Importantly, the critical step of registration quality assessment is discussed, requiring the assessment of both the image fusion and the deformation field to ensure biological plausibility.

For more information: www.mirada-medical.com

Related Content

New Data Demonstrates Safety Profile of GammaTile Therapy for Various Brain Tumors
News | Brachytherapy Systems | June 18, 2019
GT Medical Technologies Inc. announced the presentation of clinical data from a prospective study of GammaTile Therapy...
Black Men Less Likely to Adopt Active Surveillance for Low-Risk Prostate Cancer
News | Prostate Cancer | June 17, 2019
A new study reveals black men are less likely than white men to adopt an active surveillance strategy for their...
University Medical Center Groningen Performs First Automatic Log-based Proton Therapy Patient QA
News | Proton Therapy | June 14, 2019
IBA announced the physics team of University Medical Center Groningen (UMCG) in the Netherlands has developed and...
Materialise Receives FDA Clearance for Cardiovascular Planning Software Suite
Technology | Advanced Visualization | June 13, 2019
Three-dimensional (3-D) printing software and solutions company Materialise has received U.S. Food and Drug...
Medivis SurgicalAR Gets FDA Clearance
Technology | Virtual and Augmented Reality | June 10, 2019
Medivis announced that its augmented reality (AR) technology platform for surgical applications, SurgicalAR, has...
ASTRO Applauds New Prior Authorization Legislation
News | Radiation Therapy | June 07, 2019
The American Society for Radiation Oncology (ASTRO) released a statement applauding Congress’s introduction of...
IBA Dosimetry Launches myQA iON
News | Quality Assurance (QA) | June 07, 2019
IBA (Ion Beam Applications S.A.) announced the launch of myQA iON at the 2019 Particle Therapy Co-Operative Group (...
Study Identifies MRI-Guided Radiation Therapy as Growing Market Segment
News | Image Guided Radiation Therapy (IGRT) | June 06, 2019
Revenues from the magnetic resonance imaging (MRI)-guided radiation therapy systems market exceeded $220 million in...
Ann Arbor Startup Launches Augmented Reality MRI Simulator
Technology | Virtual and Augmented Reality | June 04, 2019
SpellBound, an Ann Arbor startup specializing in augmented reality (AR) tools for children in hospitals, has officially...
RefleXion Opens New Manufacturing Facility for Biology-guided Radiotherapy Platform
News | Radiation Therapy | May 31, 2019
RefleXion Medical recently announced the opening of its new manufacturing facility at its headquarters in Hayward,...