According to ARRS’ American Journal of Roentgenology (AJR), an AI tool for detection of incidental pulmonary embolus (iPE) on conventional contrast-enhanced chest CT examinations had high NPV and moderate PPV, even finding some iPEs missed by radiologists

Left: Axial image shows central nonocclusive filling defect in right lower lobe lateral subsegmental pulmonary artery (arrow). Examination classified positive for iPE by AI but negative for iPE by clinical report. Adjudication process used for reference standard determination classified examination as positive for iPE. Right: Activation map shows location corresponding with iPE identified by AI (arrow). 


July 21, 2022 — According to ARRS’ American Journal of Roentgenology (AJR), an AI tool for detection of incidental pulmonary embolus (iPE) on conventional contrast-enhanced chest CT examinations had high NPV and moderate PPV, even finding some iPEs missed by radiologists. 

“Potential applications of the AI tool include serving as a second reader to help detect additional iPEs or as a worklist triage tool to allow earlier iPE detection and intervention,” wrote lead investigator Kiran Batra from the University of Texas Southwestern Medical Center in Dallas. “Various explanations of misclassifications by the AI tool (both false positives and false negatives) were identified, to provide targets for model improvement.” 

Batra and colleagues’ retrospective study included 2,555 patients (1,340 women, 1,215 men; mean age, 53.6 years) who underwent 3,003 conventional contrast-enhanced chest CT examinations between September 2019 and February 2020 at Parkland Health in Dallas, TX. Using an FDA-approved, commercially available AI tool (Aidoc, New York, NY) to detect acute iPE on the images, a vendor-supplied natural language processing algorithm (RepScheme, Tel Aviv, Israel) was then applied to the clinical reports to identify examinations interpreted as positive for iPE. 

Ultimately, the commercial AI tool had NPV of 99.8% and PPV of 86.7% for detection of iPE on conventional contrast-enhanced chest CT examinations (i.e., not using CT pulmonary angiography protocols). Of 40 iPEs present in the team’s study sample, 7 were detected only by the clinical reports, and 4 were detected only by AI. 

Noting that both the AI tool and clinical reports detected iPEs missed by the other method, “the diagnostic performance of the AI tool did not show significant variation across study subgroups,” the authors of this AJR article added

For more information: arrs.org 


Related Content

News | Magnetic Resonance Imaging (MRI)

June 2, 2023 — Philips has entered into a collaboration with medical imaging company Polarean to advance the field of ...

Time June 02, 2023
arrow
News | Magnetic Resonance Imaging (MRI)

June 2, 2023 — Ezra, the healthcare artificial intelligence (AI) startup transforming early cancer detection through ...

Time June 02, 2023
arrow
Feature | Radiology Imaging | By Melinda Taschetta-Millane

It's been a fruitful month for itnonline.com! Here's a look at what ITN viewers found to be most interesting during the ...

Time June 01, 2023
arrow
News | Radiology Business

May 26, 2023 — HIMSS has appointed two technology executives at the helm as chair and vice chair of the HIMSS Board of ...

Time May 26, 2023
arrow
News | Computed Tomography (CT)

May 26, 2023 — GE HealthCare, a leading medical technology innovator, announced today its largest ever CT deal in the ...

Time May 26, 2023
arrow
News | Breast Density

May 25, 2023 — Researchers from the Mayo Clinic (Rochester, MN) and University of California, San Francisco confirmed ...

Time May 25, 2023
arrow
News | Ultrasound Women's Health

May 25, 2023 — According to an accepted manuscript published in ARRS’ own American Journal of Roentgenology (AJR), deep ...

Time May 25, 2023
arrow
News | Pediatric Imaging

May 24, 2023 — A new advanced form of computed tomography (CT) imaging called photon-counting computed tomography (PCCT) ...

Time May 24, 2023
arrow
News | Artificial Intelligence

May 24, 2023 — Since the launch of ChatGPT in November 2022, the use of large language models (LLMs) powered by ...

Time May 24, 2023
arrow
News | Radiology Imaging

May 19, 2023 — Asymptomatic adults with a high accumulation of fat in their muscles, known as myosteatosis, are at an ...

Time May 19, 2023
arrow
Subscribe Now