News | March 16, 2009

Five-Day Radiation Therapy of Early-Stage Prostate Cancer Shows Promise

March 16, 2009 - According to a March 15 study in the International Journal of Radiation Oncology*Biology*Physics (the official journal of ASTRO), preliminary results show that a shortened course of radiation therapy for prostate cancer called stereotactic body radiation therapy (SBRT) provides good PSA response for early-stage prostate cancer and has the same side effects as other treatments.

Study authors caution that further follow-up will be necessary to establish that SBRT is as effective in the long term as other proven treatments.

Radiation therapy is an effective way to treat localized prostate cancer. Proven successful treatments include brachytherapy (seed implants) where radiation sources are placed directly into the prostate and external beam radiation therapy where doctors give small daily doses of radiation to the prostate, five days a week, for eight weeks to give enough radiation to kill the cancer cells while sparing nearby healthy tissue.

External beam radiation therapy can be a very effective and minimally invasive treatment. However, the length of treatment can be burdensome for some patients, particularly those who live very far from a treatment facility. Doctors have been investigating ways to shorten the course of the treatment through a technique called stereotactic body radiation therapy, where radiation oncologists give a higher dose of radiation every day for five days. Growing biologic evidence also suggests that delivering radiotherapy in this fashion might be more effective for prostate cancer than conventionally protracted courses.

In this study, researchers from Stanford University treated 41 men with low-risk prostate cancer with SBRT. After a median follow-up of 33 months, no man in the study has seen his cancer return. Men in the study reported side effects, including urinary and rectal problems that were no better or worse than with other prostate cancer radiation treatments.

"There is great enthusiasm in reducing the length of treatment for prostate cancer while also possibly improving its effectiveness, and these early results are very promising for men with early-stage prostate cancer," Christopher King, Ph.D., M.D., an associate professor of radiation oncology at Stanford University School of Medicine in Stanford, CA. "However, it can often take as long as 10 years to see late side effects and recurrences, so we will have to monitor these men closely and cautiously pursue these treatments further before we can confidently say that SBRT is as good as other proven prostate cancer treatments, like external beam radiation therapy, brachytherapy or surgery."

For more information: www.astro.org

Related Content

ASTRO Applauds Introduction of PIMA Patient Protection Bill
News | Radiology Business | April 15, 2019
The American Society for Radiation Oncology (ASTRO) hailed the introduction of federal legislation that would...
Varian Discloses First Preclinical Results of Flash Therapy in Cancer Treatment
News | Proton Therapy | April 09, 2019
Varian, in partnership with the University of Maryland School of Medicine’s Department of Radiation Oncology and the...
Varian Halcyon Commissioned at MedStar Southern Maryland Hospital Center With IBA's myQA Halo
News | Quality Assurance (QA) | April 04, 2019
IBA (Ion Beam Applications S.A.) announced the successful commissioning of the Varian Halcyon at the Radiation Oncology...
Four of the top pieces of content in March included news on proton therapy, including a 360 image and videos from ITN's recent visit to the Northwestern Medicine Proton Center in the Chicago suburbs. This image shows the main proton treatment room gantry at the proton center in Warrenville, Ill. Interview with Mark Pankuch, Ph.D.

Four of the top pieces of content in March included news on proton therapy, including a 360 image and videos from ITN's recent visit to the Northwestern Medicine Proton Center in the Chicago suburbs. This image shows the main proton treatment room gantry at the proton center in Warrenville, Ill.
 

Feature | April 02, 2019 | Dave Fornell, Editor and A.J. Connell
April 2, 2019 — Here is the list of the most popular content on the Imaging Technology News (ITN) magazine w
ZON-PTC in Clinical Use With RayStation 8B and Hyperscan
News | Treatment Planning | March 19, 2019
Zuid-Oost Nederland Protonen Therapie Centrum (ZON-PTC), Maastricht, Netherlands, recently treated its first patient...
What to Expect from the Proton Therapy Market in 2019-2020
News | Proton Therapy | March 13, 2019
The number of new particle therapy rooms ordered worldwide dropped by almost 20 percent in 2018, according to a new...
Mississippi Cancer Center Combines RayStation and TomoTherapy for Prostate Cancer Case
News | Treatment Planning | March 08, 2019
Anderson Regional Cancer Center in Meridian, Miss., has treated its first patient using the combination of RaySearch's...
Videos | Proton Therapy | March 01, 2019
ITN Associate Editor Jeff Zagoudis speaks with Mark Pankuch, Ph.D., director of physics and dosimetry at the...
Videos | Proton Therapy | February 28, 2019
ITN Associate Editor Jeff Zagoudis speaks with ...