News | Cardiovascular Ultrasound | July 29, 2015

Cardiac Ultrasound Image Analysis Software Research Highlighted at ASE 2015

Epsilon Imaging's EchoInsight software used in four studies assessing echo analysis

Epsilon Imaging, EchoInsight, ASE 2015, cardiac ultrasound image analysis

June 22, 2015 — Epsilon Imaging Inc. announced that several studies were presented at the American Society of Echocardiography (ASE) 2015 conference, June 13-16, on its EchoInsight automated measurement suite for improved analysis and interpretation in echo. 

Based on the ASE guidelines, the suite includes automated linear, area and volumetric measurements designed to save time and improve standardization in echo analysis. Developed specifically for the clinical environment, EchoInsight is vendor-neutral and now includes an automated measurement suite, practical application-specific strain imaging, and rapid study comparison and trending for comprehensive assessment and patient monitoring in echo.

ASE 2015 research studies included:

  •  “The Use of Two-Dimensional Speckle-Tracking Strain in Monitoring Cardiotoxicity in Older Patients with Acute Myeloid Leukemia (AML)," presented by Nausheen Akhter, et al. from Northwestern Memorial Hospital. The study analyzed 25 AML patients enrolled in the ECOG2906 study (standard cytarabine and daunorubicin vs. clofarabine [Genzyme/Sanofi]). Echo studies were performed before and after induction of therapy. 2-D speckle-tracking echo was performed using EchoInsight. The study concluded four-chamber longitudinal strain can be used to follow cardiotoxicity in patients undergoing induction 7+3 chemotherapy. Patients treated with 7+3 were noted to have both subclinical and clinically significant changes in left ventricular (LV) function. These changes were not seen in the clofarabine group. These findings suggest that changes in LV function occur shortly after exposure to relatively low doses of anthracycline in older patients with AML. 
  • “Relation between Left Atrial (LA) Deformation Imaging in Varying Degrees of Left Ventricular (LV) Diastolic Dysfunction (DD),” presented by Amita Singh, M.D., Karima Addetia, Roberto Lang, et al., from the University of Chicago Medicine. In this study 100 age-matched patients with left ventricular ejection fraction (LVEF) >50 percent and no significant valvulopathy were assessed, including: 25 normal subjects (NL) and three groups of 25 patients each with grades 1, 2 and 3 diastolic dysfunction (DD), as defined by ASE guidelines. Mitral inflow E velocity, E-wave deceleration time, A-velocity, lateral and medial mitral annular E’ velocities, E/(mean E’), LA volumes (biplane Simpson), and 2-D speckle tracking derived LA longitudinal strain (EchoInsight) were measured throughout the cardiac cycle (and atrial stiffness defined as (E/E’/peak LA strain)).  The study concluded in subjects with LV DD and preserved EF, changes in LA deformation and stiffness with worsening DD reflect a progressive decline in LA function, which is not as easily identified by conventional Doppler and LA volume measurements. 
  • “Left Atrial Strain Predicts Atrial Fibrillation Recurrence in Patients with Persistent Atrial Fibrillation and Preserved Ejection Fraction Treated With Catheter Ablation,” presented by Mislav Vrsalovic, Theodore Kolias, et al. from University of Michigan. 92 patients with persistent atrial fibrillation (AF) and preserved EF underwent first catheter ablation (CA) and echo ≤ 30 days prior to CA. Left atrial and ventricular global longitudinal strains (GLS) were measured with 2-D speckle tracking (EchoInsight), and patients were followed for AF recurrence. The study concluded left atrial GLS is a strong and independent predictor of AF recurrence after first CA therapy in patients with persistent AF and preserved EF.
  • “Echocardiographic Evaluation Of Right Ventricular Function in Patients with McConnell’s Sign: The Added Benefits of Right Ventricular Free Wall Strain,” presented by Anuj Mediratta, Karima Addetia, Roberto Lang, et al. from University of Chicago Medicine. 156 transthoracic echocardiogram (TTE) studies were reviewed with McConnell’s sign (MS) and a diagnostic study (computed tomography or V/Q scan) was given within 48 hours to evaluate for acute pulmonary embolism (PE). Echo images were analyzed with EchoInsight to measure right ventricular (RV) fractional area change (FAC), tricuspid annular plane systolic excursion (TAPSE), early tricuspid annular velocity S’ and 2-D speckle-tracking derived RV free-wall longitudinal strain (LS) and segmental free-wall strain of apex, mid and basal RV. The study concluded that patients with MS have reduced global RV free wall strain, segmental strain including the apex. Qualitative assumption of normal RV apical function in MS is likely related more to left ventricular apex contractility with tethering of the RV apex rather than normal RV apex function. 

 

For more information: www.epsilon-imaging.com

Related Content

Ebit and DiA Imaging Analysis Partner on AI-based Cardiac Ultrasound Analysis
News | Cardiovascular Ultrasound | April 16, 2019
DiA Imaging Analysis has partnered with the Italian healthcare IT company Ebit (Esaote Group), to offer DiA’s LVivo...
360 Photos | 360 View Photos | April 12, 2019
This 360 degree view shows staff at the ...
DiA Imaging Analysis Introduces LVivo SAX Ultrasound Analysis Tool
Technology | Cardiovascular Ultrasound | April 09, 2019
DiA Imaging Analysis announced the launch of LVivo SAX, a cardiac analysis tool that helps clinicians quickly and...
SuperSonic Imagine Highlights Aixplorer Mach 30 Breast Ultrasound at SBI/ACR Breast Imaging Symposium
News | Ultrasound Women's Health | April 03, 2019
SuperSonic Imagine will introduce the new generation of its Aixplorer Mach 30 breast ultrasound solution at the 2019...
Videos | RSNA | April 03, 2019
ITN Editor Dave Fornell takes a tour of some of the most interesting new medical imaging technologies displa
Bay Labs Announces New Data on EchoGPS, AutoEF AI Software at ACC.19
News | Cardiovascular Ultrasound | March 15, 2019
Artificial intelligence (AI) company Bay Labs announced the presentation of two studies assessing performance of the...
Esaote Introduces MyLab X8 Ultrasound Platform
News | Ultrasound Imaging | March 13, 2019
Esaote announced the launch of MyLab X8, a high-performance, versatile ultrasound platform to support hospitals and...
Ultrasound Societies Urge FDA to Remove "Black Box" on Ultrasound Contrast Agents
News | Ultrasound Imaging | March 07, 2019
National and international ultrasound societies are urging the U.S. Food and Drug Administration to remove the “black...
Canon Medical Systems introduces 33 MHz Ultra-High Frequency Ultrasound Transducer
News | Ultrasound Imaging | March 01, 2019
March 1, 2019 — Expanding its advanced, high-performing Aplio i-series...