News | August 06, 2010

ASTRO Publishes Whole Breast Irradiation Guidelines

The American Society for Radiation Oncology (ASTRO) has released evidence-based guidelines to define appropriate fractionation of whole breast irradiation (WBI), finding that hypofractionated (HF) WBI is effective for many patients with early-stage breast cancer. These guidelines are published in the International Journal of Radiation Oncology Biology Physics, the official journal of ASTRO.

HF-WBI is a type of WBI that uses a higher dose for each treatment but fewer total treatments, so patients can typically finish radiation in four weeks or less. Several trials have found little difference in the local control and survival outcomes for selected patients treated with either conventionally fractionated radiation (CF-WBI) or HF-WBI.

Despite its effectiveness, conventional fractionation has some drawbacks, including the inconvenience associated with undergoing treatment for a long period of time.

The task force concluded that HF-WBI is just as effective as CF-WBI for early-stage breast cancer patients who meet specific criteria. These criteria include age 50 years and older, stage T1-2 N0, not receiving chemotherapy, relatively uniform delivery of the radiation dose and the ability to exclude the heart from the path of the radiation beam.

"Widespread adoption of HF-WBI for appropriately selected patients has the potential to enhance the convenience of treatment and lower the costs of WBI," Benjamin D. Smith, M.D., lead author of the study and a radiation oncologist at the University of Texas M.D. Anderson Cancer Center in Houston, said. "For patients where the data to support HF-WBI are not as strong, HF-WBI can still be considered an option but further research is needed."

For more information: www.rtanswers.org, www.astro.org

Related Content

UFHPTI expands its proton therapy capacity and treatment range with the Proteous One
News | Radiation Therapy | December 12, 2019
December 12, 2019 — IBA (Ion Beam Applications SA) announced that

Image courtesy of Elekta 

News | Radiation Therapy | December 11, 2019
December 11, 2019 — A new clinical guideline from the American Soci...
RaySearch Laboratories AB (publ) has experienced strong growth in recent years, creating the need for larger and more efficient premises
News | Radiation Therapy | December 09, 2019
December 9, 2019 — Karin Gedda, architect and i
Timothy Whelan is a professor of oncology at McMaster University and a radiation oncologist at the Juravinski Cancer Centre of Hamilton Health Sciences. He holds a Canada Research Chair in Breast Cancer Research. Photo courtesy McMaster University

Timothy Whelan is a professor of oncology at McMaster University and a radiation oncologist at the Juravinski Cancer Centre of Hamilton Health Sciences. He holds a Canada Research Chair in Breast Cancer Research. Photo courtesy McMaster University. Photo courtesy of McMaster University

News | Breast Imaging | December 06, 2019
December 6, 2019 — A shorter course of higher-dose radiation treatment to part of the breast is showing promise in wo
#RSNA19 GE Healthcare introduced Serena Bright, the healthcare industry’s first contrast-enhanced mammography solution for biopsy
News | Mammography | November 30, 2019
November 30, 2019 — To help empower clinicians and patients in their fight against...
This bar graph shows breast cancer presentation by screening interval #RSNA19

This bar graph shows breast cancer presentation by screening interval. Image courtesy of study author and RSNA

News | Breast Imaging | November 28, 2019
November 28, 2019 — Cancers found in patients undergoing annual...
News | Breast Imaging | November 26, 2019
November 26, 2019 — Unifi Workspace, a new comprehensive breast diagnostic reading solution from Hologic, will launch
Candelis, Inc. recently launched the Advanced Breast Imaging Workstation as an enhancement to its ImageGrid platform
News | Breast Imaging | November 22, 2019
November 22, 2019 — Candelis, Inc. recently launched the Adv