Technology | April 12, 2013

Aspect Imaging LumiQuant Enables Tomographic Quantification of Luminescence Using Compact MRI Platform

Hardware and software solution provides new multi-modality insights

Bruker Icon

April 12, 2013 — Aspect Imaging launched LumiQuantits software and hardware solution for co-registering and measuring luminescence imaging images with the Bruker Icon compact high-performance magnetic resonance imaging (MRI) system. The LumiQuant solution enables researchers to generate 3-D luminescence data co-registered with MRI, a path forward in multi-modal tomographic imaging.

LumiQuant leverages a multi-modality cassette that allows a mouse to be imaged in an optical instrument and then moved and imaged in the Bruker Icon compact MRI without perturbation. The image reconstruction and co-registration package uses a proprietary set of algorithms to create a three-dimensional distribution of luminescence signal.

Luminescence, which is the most widely used pre-clinical in vivo imaging modality for assessing pre-clinical disease models, suffers from the physical constraints of the absorption and scattering of light in tissues. This absorption and scattering hinders the ability of luminescence systems to differentiate between luminescence signal in different organs and on the surface or signal deep within the tissue and therefore limits the researcher's ability to tell whether a luminescence-expressing tumor, for example, is on the surface, is deep in the organ, is a single tumor mass or possibly is the signal expressed from multiple lesions at different positions in the body. LumiQuant seeks to resolve this obstacle through enhanced insights and quantitation of 3-D luminescence/MR imaging and disease phenotyping.

For more information: www.aspectimaging.com, www.invicro.com

Related Content

Technology | Focused Ultrasound Therapy | June 19, 2018
EDAP TMS SA has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Focal One device for...
3D Systems Announces On Demand Anatomical Modeling Service
Technology | Medical 3-D Printing | June 18, 2018
3D Systems announced availability of its new On Demand Anatomical Modeling Service. This new service provides a wide...
Elekta Unity High-Field MR-Linac Receives CE Mark
News | Image Guided Radiation Therapy (IGRT) | June 18, 2018
Elekta announced that its Elekta Unity magnetic resonance radiation therapy (MR/RT) system has received CE mark,...
Washington University in St. Louis Begins Clinical Treatments With ViewRay MRIdian Linac
News | Image Guided Radiation Therapy (IGRT) | June 14, 2018
June 14, 2018 — The Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in S
Technology | Orthopedic Imaging | June 13, 2018
EOS imaging announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its hipEOS...
Reduced hippocampal volume on MRI

This figure shows reduced hippocampal volume over the course of 6 years as seen on progressive volumetric analysis and also coronal MRI evaluations (arrows).Progressive volume loss in the mesial temporal lobe on MRI is a characteristic imaging feature of AD. This patient was a case of Alzheimer’s Dementia.

 

News | Neuro Imaging | June 12, 2018
According to a UCLA Medical Center study, a new technology shows the potential to help doctors better determine when...
High Prevalence of Atherosclerosis Found in Lower Risk Patients
News | Magnetic Resonance Imaging (MRI) | June 08, 2018
Whole-body magnetic resonance angiography (MRA) found a surprisingly high prevalence of atherosclerosis in people...
Philips Receives FDA 510(k) for Ingenia Elition MR System
Technology | Magnetic Resonance Imaging (MRI) | June 07, 2018
Philips announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its...
FDA Issues Proposed Order to Reclassify Certain Radiological Medical Image Analyzers
News | Computer-Aided Detection Software | June 01, 2018
The U.S. Food and Drug Administration (FDA) is issuing a proposed order to reclassify certain radiological medical...
Researchers Use Radiomics to Overcome False Positives in Lung Cancer CT Screening
News | Advanced Visualization | May 29, 2018
A team of researchers including investigators from Mayo Clinic has identified a technology to address the problem of...
Overlay Init