Paradromics, Siemens Healthineers to Collaborate on Multimodal Imaging Platform

Oct. 19, 2026 — Paradromics Inc. has announced a collaboration with Siemens Healthineers to develop an advanced multimodal imaging platform designed to support the growing clinical use of implantable brain-computer interfaces (BCIs).

The companies will develop an integrated imaging approach spanning the continuum of BCI care, from patient candidacy assessment and neural target identification through surgical planning, intraoperative navigation, post-implant localization, neural validation of functional imaging findings, and outcomes assessment.

The brain is organized into highly specialized but interconnected regions that support functions such as speech, language, movement, vision, hearing and cognition. Because the location and organization of these functional areas can vary from person to person, accurately mapping them before implantation is critical to identifying the best target for each patient.

Brain-computer interfaces are advancing from academic proof-of-concept research toward clinical systems capable of restoring functions such as communication and computer control. As these systems become more sophisticated, accurately identifying the areas of the brain responsible for speech, movement and other functions becomes increasingly important to device performance and patient outcomes.

Developing a Multimodal Platform

"Building the best hardware is only part of the story. BCI performance begins before an implant ever reaches the brain," said Matt Angle, Ph.D., founder and CEO of Paradromics. "The ability to understand each patient's individual anatomy and functional organization can help us identify the right neural target and place our technology with greater accuracy. Working with Siemens Healthineers will help us streamline this process prior to surgery, so that patients get the best possible outcome."

Building on standard imaging protocols already used by Paradromics on Siemens Healthineers scanners, the companies intend to develop an optimized end-to-end imaging package encompassing image acquisition, co-registration and processing, surgical-navigation-ready outputs, and increasingly automated analysis. The goal is to create an approach that can ultimately be deployed efficiently across medical centers using Siemens Healthineers imaging systems.

The planned workflow will integrate multiple imaging modalities, including structural MRI, functional MRI, vascular imaging and CT. Together, these technologies can help clinical teams assess brain anatomy, identify functionally relevant regions, plan surgical trajectories, avoid critical vascular structures, and determine the final location of implanted BCI components.