December 23, 2008 - The risk of developing lymphedema is 40 percent to 60 percent higher in women with body mass index (BMI) classified as overweight or obese compared to normal weight women, according to a new study by researchers at the University of Missouri (MU).
Researchers in the study, "Post-Op Swelling and Lymphoedema Following Breast Cancer Treatment," which was published in the Journal of Lymphoedema (Vol. 3, No. 2), recommended increased health education for breast cancer survivors.
“Breast cancer survivors with high BMIs will benefit from education focused on maintaining optimal BMI and lymphedema risk reduction practices,” said Jane Armer, professor in the Sinclair School of Nursing and director of nursing research at the Ellis Fischel Cancer Center. “Overweight women have the greatest risk of developing lymphedema and should be monitored closely for changes in symptoms and limb volume, especially those who have cancer treatment to the dominant side or experience post-operation swelling.”
Based on the analysis, lymphedema is a risk for approximately two-thirds of breast cancer survivors in the 30 months after surgery. Breast cancer survivors who develop post-op swelling have a significantly higher risk (40 percent) of developing lymphedema. According to Armer, patients with high BMIs who experience post-op swelling or were affected by cancer on their dominant side have the highest risk of developing lymphedema. MU researchers found that comparing BMI and limb volume measurements can help clinicians better detect lymphedema.
"Diagnosing post-breast cancer lymphedema can be difficult because of inconsistent measurement approaches and standards of measurement reliability and validity,” Armer said. “Pre-op limb volume measurement is an essential reference for post-op volume comparison and detection of post-op swelling. Clinicians should consider using a 5 percent limb volume change (LVC) approach (beyond change in BMI) as a more sensitive estimation of post-breast cancer lymphedema.”
For more information: munews.missouri.edu
January 29, 2026 
