News | July 08, 2009

Palliative RT Prolongs Survival in Patients with EHC

July 8, 2009 - RT prolongs survival in patients with extrahepatic cholangiocarcinomas (EHC) are rare tumors of the biliary tree, according to a study published in International Journal of Radiation Oncology - Biology - Physics.*

The researchers set out to examine the role of adjuvant and palliative RT in the treatment of EHC in a large patient population, by doing a retrospective analysis of 4,758 patients with EHC collected from the Surveillance, Epidemiology and End Results database. The primary endpoint was overall survival.

Twenty-eight percent of the patients underwent surgery, 10 percent radiation therapy (RT), 14.7 percent underwent both surgery and RT, and 46.4 percent had neither RT or surgery. The median age of the patient population was 73 years (range, 23–104), 52.5 percent were men, and 80.7 percent were white. The median overall survival time was 16 months, 9 months, and 4 months for surgery and RT, surgery, RT, and no RT or surgery, respectively. The overall survival was significantly different between the surgery and surgery and RT groups (p

These results suggest that palliative RT prolongs survival in patients with EHC. The benefit associated with surgery and RT was significant on univariate analysis but not after controlling for potential confounders using the propensity score. Future studies should evaluate the addition of chemotherapy and biologic agents for the treatment of EHC.

*Int J Radiat Oncol Biol Phys. 2009 Jun 16;74(4):1-5, ET Shinohara, M Guo, JM Metz

For more information: www.redjournal.org

Related Content

MedStar Georgetown Proton Center Selects RayStation for Treatment Planning
News | Treatment Planning | August 17, 2017
August 17, 2017 — The proton center at MedStar Georgetown University Hospital will utilize RayStation for planning on
DOSIsoft Releases ISOgray Proton Therapy Treatment Planning System
Technology | Treatment Planning | August 15, 2017
DOSIsoft SA announced the official release, with CE marking, of ISOgray Treatment Planning System (TPS) release 4.3 for...
First Radixact Results Presented at AAPM 2017
News | Radiation Therapy | August 10, 2017
Accuray Inc. announced that the first studies validating the benefits of the Radixact System were presented at the 59th...
Clinical Data Supports Use of Xoft System for Endometrial Cancer
News | Brachytherapy Systems | August 03, 2017
Researchers presented clinical data supporting use of the Xoft Axxent Electronic Brachytherapy (eBx) System for the...
Aktina’s interchangeable cones are lightweight and extremely accurate
News | Radiation Therapy | August 02, 2017
Aktina Medical announced a collaboration with Philips Medical Systems and Elekta Instruments for SRS interlocking at...
News | Image Guided Radiation Therapy (IGRT) | July 31, 2017
Elekta’s magnetic resonance radiation therapy (MR/RT) system will be the subject of 21 abstracts at the 59th American...
Accuray Receives 510(k) Clearance for iDMS Data Management System
Technology | Oncology Information Management Systems (OIMS) | July 31, 2017
July 31, 2017 — Accuray Inc. announced it has received 510(k) clearance from the U.S.
more healthcare providers and patients are choosing options such as Gamma Knife stereotactic radiosurgery
News | Radiation Therapy | July 31, 2017
Each year, up to 650,000 people who were previously diagnosed with various forms of cancer will develop brain...
Overlay Init