Technology | April 08, 2008

Multispectral Imaging System Allows for Early-Stage Evaluation

A new digital system for fluorescent multispectral optical molecular imaging, the Kodak In-Vivo Multispectral Imaging System FX, enables life science researchers to study molecular abnormalities that are the origin of disease at a very early stage.

The system is designed to precisely locate and monitor changes in molecular activity of specific cells or organs.
The imaging system’s multispectral tuning of excitation light enhances image sensitivity, allowing for the identification and separation of multiple optical (e.g., fluorescent) biological marker signals in subjects such as small animals, while removing background noise (autofluorescence). Software, native to the system, automatically generates and analyzes a series of images taken at different wavelengths with spatially coregistered X-Ray and white light images for improved localization of biomarkers in vivo. Also, the system’s multimodal capabilities include bioluminescence and radioisotopic signal detection, giving researchers a wide range of options for precisely identifying biomarkers of interest in small animals.

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