News | June 12, 2009

Breast MRI, Lymph Nodes Good Indicators of Breast Cancer

June 12, 2009 - Enlargement and abnormalities of axillary sentinel lymph nodes located in the armpit area near the breast are predictive of cancer, according to initial research conducted at University of Florida Shands Cancer Center and published in the Journal of Magnetic Resonance Imaging. What more accurately indicates the spread of disease is the loss of a key part of a normal node's structure called the fatty hilum that more accurately signals the spread of disease, not the size of the node or enhancement. "We found that the loss of fatty hilum in an axillary lymph node on MRI correlated with finding the spread of breast cancer in axillary nodes at the time of surgery," said Stephen Grobmyer, M.D., an assistant professor of surgical oncology and endocrine surgery at the UF College of Medicine, who noted that not all nodes without fatty hilum necessarily had cancer. The findings also reinforce the value of using MRI to determine the extent of breast cancer prior to surgery, which is capable of detecting more than 95 percent of invasive breast cancers. The UF study retrospectively examined 56 female patients ranging in age from 30 to 82. All women had a sentinel lymph node biopsy. Fifteen women had cancer in the nodes that required complete removal. Four of eight patients in whom a loss of fatty hilum was seen in an axillary node on MRI were found to have cancerous lymph nodes at the time of their breast surgery. By comparison, only 11 out of 48 patients, or 23 percent, with all fatty hilum in place had cancer. For more information: www.health.ufl.edu

Related Content

Left to right: Subtraction right mediolateral oblique (MLO) CEM was non-diagnostic because of artifact, potentially due to motion misregistration from extended exposure time; subtraction right MLO implant displaced CEM image shows 5.8 cm enhancing mass (arrow); contrast-enhanced MRI sagittal subtraction image shows concordant mass (arrow).

Left to right: Subtraction right mediolateral oblique (MLO) CEM was non-diagnostic because of artifact, potentially due to motion misregistration from extended exposure time; subtraction right MLO implant displaced CEM image shows 5.8 cm enhancing mass (arrow); contrast-enhanced MRI sagittal subtraction image shows concordant mass (arrow).

News | Breast Imaging | March 18, 2021
March 18, 2021 — 
Breast cancer is the most common fatal cancer in women. Early detection increases a woman's chances of recovery. Magnetic Resonance Imaging (MRI) is an accurate technique for detecting and classifying tumors in breast tissue.
News | MRI Breast | March 09, 2021
March 9, 2021 — Breast cancer is the most common fatal cancer in women.
A comparison of standard mammography imaging (left) in a woman with dense breasts and a breast MRI imaging study (right) showing a clearly defined cancer and is extremely hard to detect on the mammograms.

A comparison of standard mammography imaging (left) in a woman with dense breasts and a breast MRI imaging study (right) showing a clearly defined cancer and is extremely hard to detect on the mammograms. Images from Christiane Kuhl, M.D.

Feature | MRI Breast | March 04, 2021 | By Dave Fornell, Editor
Dense breast tissue can hide cancers i
A, Contrast-enhanced axial T1-weighted fat-saturated image from baseline MRI before initiation of neoadjuvant therapy shows irregular mass (arrow) in upper inner right breast corresponding to biopsy-proven carcinoma. B, Contrast-enhanced axial T1-weighted fat-saturated image from follow-up MRI performed 3 months after initiation of neoadjuvant therapy shows decrease in size of right breast cancer (arrow). C, Contrast-enhanced axial T1-weighted fat-saturated image 3 months after initiation of neoadjuvant the

A, Contrast-enhanced axial T1-weighted fat-saturated image from baseline MRI before initiation of neoadjuvant therapy shows irregular mass (arrow) in upper inner right breast corresponding to biopsy-proven carcinoma. B, Contrast-enhanced axial T1-weighted fat-saturated image from follow-up MRI performed 3 months after initiation of neoadjuvant therapy shows decrease in size of right breast cancer (arrow). C, Contrast-enhanced axial T1-weighted fat-saturated image 3 months after initiation of neoadjuvant therapy shows new mass (arrow) in upper outer left breast that was assessed as BI-RADS 4. Pathologic examination from MRI-guided core biopsy of new suspicious mass revealed benign usual ductal hyperplasia. No atypia or malignancy was identified. Image courtesy of American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)

News | MRI Breast | January 15, 2021
January 15, 2021 — According to ARRS' ...
Earlier initial diagnosis reduces lung cancer mortality in heavy (ex-)smokers / The risk of harm from misdiagnosis or overdiagnosis is relatively low

Image courtesy of Toshiba/Canon

News | Computed Tomography (CT) | December 08, 2020
December 8, 2020 — For heavy (ex-)smokers,...
Reduces the complexity of reporting for screening and diagnostic MRI eams to deliver time-saving and patient safety benefits
News | MRI Breast | November 18, 2020
November 18, 2020 — ...
Murray Rebner, M.D., performing a breast ultrasound. Image courtesy of Beaumont Health

Murray Rebner, M.D., performing a breast ultrasound. Image courtesy of Beaumont Health

News | Breast Imaging | November 02, 2020
November 2, 2020 — Though Black women get ...
Study of Penn Medicine patients shows abbreviated MRI may be a valuable supplemental screening for women with dense breasts
News | MRI Breast | October 28, 2020
October 28, 2020 — Beth Reisboard, 76, was relieved in 2018 when she received the results from her annual...
Mammography, which is an X-ray picture of the breast, is efficient also for women over the age of 70.

Getty Images

News | Mammography | October 22, 2020
October 22, 2020 — ...