MultiHance (gadobenate dimeglumine) is indicated for intravenous use in MRI of the CNS in adults to visualize lesions with abnormal blood brain barrier or abnormal vascularity of the brain, spine, and associated tissues.

MultiHance is a Magnetic Resonance Imaging (MRI) contrast agent that has nearly twice the relaxtivity of other gadolinium-based contrast agents providing a marked increase in Signal-to-Noise Ratio (SNR) in T1-weighted images. Unlike other paramagnetic contrast agents, MultiHance reportedly demonstrates weak and transient interactions with serum proteins that causes slowing in the molecular tumbling dynamics, resulting in strong increases in relaxivity in solutions containing serum proteins. The improved relaxation effect could potentially contribute to improved visualization.

Bracco launched MultiHance in Europe in 1998 and received FDA approval to market in the US in 2004, with over 3.5 million doses used worldwide.


Related Content

News | Interventional Radiology

November 3, 2023 — Guerbet, a global leader in medical imaging with more than 30 years of experience in MRI, announced ...

Time November 03, 2023
arrow
News | Magnetic Resonance Imaging (MRI)

October 17, 2023 — Halo Precision Diagnostics, a leader in early disease detection using precision diagnostics, today ...

Time October 17, 2023
arrow
News | Ultrasound Imaging

September 15, 2023 — Contrast enhanced ultrasound (CEUS) is underutilized in the United States, and reduced access to ...

Time September 15, 2023
arrow
News | Prostate Cancer

July 28, 2023 — Blue Earth Diagnostics, a Bracco company and recognized leader in the development and commercialization ...

Time July 28, 2023
arrow
News | Magnetic Resonance Imaging (MRI)

July 27, 2023 — Scientists have found a new use for copper in magnetic resonance imaging (MRI) contrast agent design ...

Time July 27, 2023
arrow
News | Contrast Media

July 25, 2023 — Bracco Imaging has issued a statement on new results published in the journal Radiology which found that ...

Time July 25, 2023
arrow
News | Contrast Media

June 20, 2023 — Ascelia Pharma presented data from its Orviglance Hepatic Impairment study during the European Society ...

Time June 20, 2023
arrow
News | Contrast Media

May 16, 2023 — Bracco Imaging, an innovative world leader delivering end-to-end products and solutions through a ...

Time May 16, 2023
arrow
News | Contrast Media

May 15, 2023 — Guerbet, a global leader in medical imaging with more than 30 years of experience in MRI, announced that ...

Time May 15, 2023
arrow
Feature | Contrast Media | By Christine Book

In the past year, the radiology community has been a first-hand, hands-on witness to myriad unexpected challenges and ...

Time May 03, 2023
arrow
Subscribe Now