Technology | April 23, 2009

3T MRI Detects "Early" Breast Cancer Not Seen On Mammography, Ultrasound

April 23, 2009 - 3T MRI can detect a significant number of lesions not found on mammography and sonography, according to a study performed at the University of Toledo Medical Center, Toledo, OH.

The study included 434 women who underwent mammography, sonography and 3T MRI for the detection of malignant breast lesions-all women were at high risk. Results showed that 3T MRI detected 66/66 malignant lesions; mammography detected 54/66 malignant lesions; and sonography detected 57/66 malignant lesions. "3T MRI depicted a significantly higher number of malignant tumors of the breast than mammography and sonography," said Haitham Elsamaloty, M.D., lead author of the study.

"Our study detected 'early' breast cancer (lesions as small as 4 mm) in size and also identified malignant lesions that were only detected by MRI and confirmed by MRI guided biopsy. These crucial findings led to a significant change in patient management in 18.2 percent of the cases in our study.

"Our study suggests an important role for 3T MRI in such high risk groups for an early diagnosis of breast cancer and better accuracy in evaluating the extent of disease-a crucial factor in appropriate therapy planning," said Dr. Elsamaloty.

"High field strength (3T) MRI systems are becoming increasingly available in the clinical setting and more of them are being used for the evaluation of breast malignancy. 3T MRI is an important addition to mammography and sonography," he said.

Source: This study appears in the April issue of the American Journal of Roentgenology.

For more information: www.ajronline.org

Related Content

Sponsored Content | Videos | Breast Imaging | July 28, 2017
Nancy Cappello, Ph.D., executive director and founder of Are You Dense Inc. and Are You Dense Advocacy, explains how
MRI Plus Mammography Improves Detection of New Breast Cancer After Surgery
News | Breast Imaging | June 22, 2017
A new article published by JAMA Oncology compares outcomes for combined mammography and magnetic resonance imaging (MRI...
Radiology journal, breast MRI screening, average risk women, breast cancer

Images in a 55-year-old screening participant. (a, b) Normal digital full-field mediolateral oblique (a) and craniocaudal (b) mammograms (BI-RADS category 1) show a heterogeneously dense breast (ACR category C). (c) Screening ultrasound image shows normal findings (BI-RADS category 1). (d) MR-guided biopsy enabled us to confirm the presence of an invasive high-grade triple-negative cancer (no special type [NST], pT1b, N0, M0). (d) Breast MR image shows a suspicious enhancing mass (arrow) in the left breast (BI-RADS category 5). Image courtesy of the Radiological Society of North America.

News | MRI Breast | February 21, 2017
Magnetic resonance imaging (MRI) screening improves early diagnosis of breast cancer in all women, not only those at...
Rapid Breast MRI, breast cancer screening, David Strahle, RMI, Breast Cancer Research and Treatment study
News | MRI Breast | February 10, 2017
February 10, 2017 — A new method for screening women with dense breast tissue may potentially save thousands of lives
breast MRI, new AB-MR exam protocol, Via Radiology, cancer detection, dense breasts, women's health
News | MRI Breast | February 07, 2017
A newly developed breast magnetic resonance imaging (MRI) exam protocol, the first of its kind being offered in the...
News | MRI Breast | June 27, 2016
A new phase 1 clinical trial from Brigham and Women's Hospital published in Radiology on June 22 evaluated the...
breast MRI, ER-positive breast cancer detection, Case Western Reserve study

Differences in dynamic textural patterns are apparent between a patient with a low recurrence score, left, and a patient with a high recurrence score, right. Image courtesy of Nature Scientific Reports

News | MRI Breast | February 19, 2016
February 19, 2016 — A new way to analyze magnet...

Molecular imaging of the GRPR biomarker on mice xenografted with PC3 and H441 cells by T1-weighted spin echo MR imaging and NIR imaging.

News | Magnetic Resonance Imaging (MRI) | December 29, 2015
December 29, 2015 — A method to better trace changes in cancers and treatment of the prostate and lung without the li
Overlay Init