Sept. 10, 2025 — ZAP Surgical Systems, Inc. will make its debut at the 2025 ASTRO (American Society for Radiation Oncology) Annual Meeting, Sept. 28 – Oct. 1 in San Francisco, Calif. ZAP Surgical will showcase the ZAP-X Gyroscopic Radiosurgery platform alongside its internationally recognized, award-winning ZAP-Axon Radiosurgery Planning System*.
Attendees will have the opportunity to explore a near full-scale model of the ZAP-X system, a dedicated cranial radiosurgery (SRS) innovation that eliminates the need for radiation-shielded vaults and replaces outdated Cobalt-60 sources with advanced linear accelerator technology.
Live demonstrations of the ZAP-Axon planning software will also be available, offering a hands-on look at ZAP’s next-generation approach to stereotactic radiosurgery (SRS) planning.
“With its dedicated cranial SRS design, ZAP-X empowers radiation oncologists to efficiently deliver the highest quality care without the compromises commonplace with multi-purpose radiation delivery systems,” said John R. Adler, MD, founder and CEO of ZAP Surgical, and Emeritus Dorothy & TK Chan Professor of Neurosurgery and Radiation Oncology at Stanford University.
The ZAP-X system leverages gyroscopic mobility to deliver radiosurgical beams from thousands of unique angles, enhancing dose shaping and aiding the sparing of healthy brain tissue and critical structures. This high-precision approach not only helps reduce treatment-related risk but also aims to better preserve mental function in patients undergoing brain radiosurgery.
“Focusing solely on conformality and dose gradient in cranial radiosurgery is outdated thinking. Recent studies reveal that multi-purpose radiotherapy systems can expose significantly more healthy brain tissue to unnecessary radiation, which early evidence suggests may lead to deleterious effects such as neurocognitive decline,” said Dr. Adler. “That’s a profoundly important distinction. Emerging research confirms that even low doses to healthy brain tissue significantly changes brain function.”
For additional general information, please visit www.zapsurgical.com.
* The ZAP-Axon Radiosurgery Planning System is pending US FDA 510(k) clearance and EU CE mark declaration.
October 15, 2025 
