The iCad Secondlook (end-result pictured) appears to be roundly beaten by AccuDetect Galileo, according to findings from a recent study.

March 9, 2012 — Parascript, LLC, an image analysis and pattern recognition technology provider, announced that its AccuDetect Galileo computer-aided detection (CAD) software for digital mammography showed better overall performance in detecting breast cancer against iCad’s SecondLook in a recent retrospective study.

Findings from the study, performed at the Maastricht University Medical Center departments of Radiology and Surgery in the Netherlands, with collaboration from University of Udine’s Institute of Diagnostic Radiology in Italy, were presented at the 2012 meeting of the European Society of Radiology (ECR).

In the study, digital mammograms of 326 patients were analyzed (117 patients with biopsy proven breast cancer, 209 negative cases) using AccuDetect Galileo 4.0 and SecondLook version 7.2. AccuDetect Galileo significantly increased true positive fraction (TPF) of cancer cases when compared to SecondLook. It demonstrated a per image increase of 6.9 percent to 72.2 percent; per case increase of 4.3 percent to 84.6 percent. The University of Maastricht team noted that AccuDetect Galileo had a significant performance improvement in detecting soft tissue densities on extremely dense breasts (BI-RADS breast density class 4) over SecondLook, increasing TPF by 15.4 percent to 69.2 percent. Dense breast tissue can obscure an underlying cancer, or conversely mimic one that does not exist, thus making accurate detection difficult.

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