PET Imaging

Positron emission tomography (PET) is a nuclear imaging technology (also referred to as molecular imaging) that enables visualization of metabolic processes in the body. The basics of PET imaging is that the technique detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (also called radiopharmaceuticals, radionuclides or radiotracer). The tracer is injected into a vein on a biologically active molecule, usually a sugar that is used for cellular energy. PET systems have sensitive detector panels to capture gamma ray emissions from inside the body and use software to plot to triangulate the source of the emissions, creating 3-D computed tomography images of the tracer concentrations within the body.

a) Includes scintigraphy and PET with and without concomitant CT. b) Includes conventional radiography, dual-energy x-ray absorptiometry, fluoroscopy, and radiography performed during radiologic interventions. c) Includes general, cardiothoracic, maxillary, plastic, and orthopedic surgery and neurosurgery. d) Includes allergology, cardiology, geriatrics, general internal medicine, pulmonology, gastroenterology, and rheumatology
News | Radiology Imaging
Unread Second-opinion Radiology Reports Waste Healthcare Resources

August 14, 2020 — According to ARRS' American Journal of Roentgenology (AJR), clinicians do not read a considerable ...

Time August 14, 2020
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Tau (blue) and amyloid (orange) distribution patterns for super-agers, normal-agers and MCI patients, when compared to a group of younger, healthy, cognitively normal, amyloid-negative individuals. Brain projections are depicted at an uncorrected significance level of p < .0001. Color bars represent the respective t-statistic. Image courtesy of Merle C. Hoenig, Institute for Neuroscience and Medicine II - Molecular Organization of the Brain, Research Center Juelich, Juelich, Germany, and Department of Nucle
News | PET Imaging
SNMMI Image of the Year Features Super-agers

July 16, 2020 — Super-agers, or individuals whose cognitive skills are above the norm even at an advanced age, have been ...

Time July 16, 2020
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Novel imaging agent provides foundation to inform treatment strategies
News | PET Imaging
Molecular Imaging Identifies Link Between Heart and Kidney Inflammation After Heart Attack

July 16, 2020 — Whole body positron emission tomography (PET) has, for the first time, illustrated the existence of ...

Time July 16, 2020
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PSMA PET/CT accurately detects recurrent prostate cancer in 67-year-old man. 18F-DCFPyL-PSMA PET/CT shows extensive, intensely PSMA-avid local recurrence in prostate (bottom row; solid arrow) in keeping with the known tumor recurrence in the prostate. Right: PET shows extensive, intensely PSMA-avid local recurrence in prostate (top row; solid arrow) and a solitary bone metastasis in left rib 2 (bottom row; dotted arrow). Image courtesy of Ur Metser, et al.
News | PET-CT
PSMA PET/CT Can Change Management in Recurrent Prostate Cancer

July 16, 2020 — New research confirms the high impact of PSMA PET/CT in the detection and management of recurrent ...

Time July 16, 2020
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Total-body dynamic 18F-FDG PET imaging with the uEXPLORER scanner allows us to monitor the spatiotemporal distribution of glucose concentration in metastatic tumors in the entire body (a). As compared to a typical clinical standardized uptake value image (b), the parametric image of FDG influx rate (Ki) can achieve higher lesion-to-background (e.g., the liver) contrast. In addition to glucose metabolism imaging by Ki, total-body dynamic PET also enables multiparametric characterization of tumors and organs
News | PET Imaging
Total-body Dynamic PET Successfully Detects Metastatic Cancer

July 16, 2020 — Results from the first study using uEXPLORER to conduct total-body dynamic positron emission tomography ...

Time July 16, 2020
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PET/CT imaging showing uptake and retention of 86Y-NM600 (imaging agent) in immunocompetent mice bearing prostate tumors. PET imaging data was employed to estimate tumor dosimetry and prescribe an immunomodulatory 90Y-NM600 (therapy agent) injected activity. Image courtesy of R Hernandez et al., University of Wisconsin-Madison, WI.
News | PET-CT
Targeted Radionuclide Therapy Enhances Prostate Cancer Response to Immunotherapies

July 15, 2020 — Targeted radionuclide therapy has been found to create a favorable tumor microenvironment in prostate ...

Time July 15, 2020
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Representative maximum-intensity projection PET images of a healthy human volunteer injected with 64Cu-NOTA-EB-RGD at 1, 8, and 24 hours after injection. Axial MRI and PET slices of glioblastoma patient injected with 64Cu-NOTA-EB-RGD at different time points after injection. Image courtesy of Jingjing Zhang et al., Peking Union Medical College Hospital, Beijing, China/ Xiaoyuan Chen et al., Laboratory of Molecular Imaging and Nanomedicine, NIBIB/NIH, Bethesda, USA
News | PET Imaging
New PET Radiotracer Proven Safe in Imaging Malignant Brain Tumors

July 15, 2020 — A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual ...

Time July 15, 2020
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Adult male with decades of right neck pain, discomfort and tightening following birth injury. The patient had failed multiple standard therapeutic maneuvers before presenting for 18F-FDG PET/MR imaging. Images shows abnormally elevated FDG uptake (white arrows; SUVmax = 1.2) observed in a linear pattern in the space in the posterolateral right neck, between the oblique capitis inferior and the semispinalis capitis muscles, where the greater occipital nerve resides. By comparison, the same region on the cont
News | SNMMI
New PET/MRI Approach Pinpoints Chronic Pain Location, Alters Management

July 14, 2020 — A new molecular imaging approach utilizing 18F-FDG positron emission tomography (PET) and magnetic ...

Time July 14, 2020
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Left: Total-body PET/CT in psoriatic arthritis: multiple joints affected, shoulders, elbows, wrists, knees, ankles and small joints of the hands/feet. Arrow: left wrist; arrowhead: right wrist. Middle: Total-body PET/CT in rheumatoid arthritis: multiple joints affected, right shoulder, small joints of the left hand. Arrowhead at the 4th proximal interphalangeal joint shows classic ring-like uptake pattern. Arrow on the foot images demonstrates the hammer toe deformity besides big toe arthritis. Right: Total
News | SNMMI
Total-body PET/CT Captures Full Picture of Systemic Inflammatory Arthritis

July 14, 2020 — For the first time, physicians can examine the systemic burden of inflammatory arthritis simultaneously ...

Time July 14, 2020
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The FDA has approved Lilly’s TAUVID (flortaucipir F 18 injection), a radioactive diagnostic agent, for PET imaging of the brain to estimate the density and distribution of aggregated tau neurofibrillary tangles (NFTs) in adult patients with cognitive impairment who are being evaluated for Alzheimer’s disease
News | Contrast Media
FDA Approves TAUVID for Use in Patients Being Evaluated for Alzheimer’s Disease

June 1, 2020 — TAUVID, a radioactive diagnostic agent, has been approved by the FDA for positron emission tomography ...

Time June 01, 2020
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MERCK and RefleXion Medical announced a collaboration to evaluate KETRUDA (immunotherapy) with biology-guided radiotherapy - BgRT -  a new radiation machine developed to treat all stages of cancer.
News | Radiation Therapy
RefleXion Announces Clinical Collaboration to Evaluate Biology-guided Radiotherapy

June 1, 2020 — RefleXion Medical, a therapeutic oncology company pioneering biology-guided radiotherapy (BgRT) for ...

Time June 01, 2020
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New radiopharmaceutical intended for PET imaging of metastatic breast cancer patients
News | Molecular Imaging
PETNET Solutions and Zionexa USA Announce FDA Approval of Cerianna

May 27, 2020 — PETNET Solutions, Inc., a Siemens Healthineers company, and Zionexa USA, a wholly owned subsidiary of ...

Time May 28, 2020
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Colored areas of the brain represent regions where the loss of brain synapses in people with early-stage Alzheimer’s was greater than people with normal cognitive function.
News | PET Imaging
New Imaging Tool Helps Researchers See Extent of Alzheimer's Early Damage

May 14, 2020 — New imaging technology allows scientists to see the widespread loss of brain synapses in early stages of ...

Time May 14, 2020
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 Siemens Healthineers has received clearance from the Food and Drug Administration (FDA) for its AIDAN artificial intelligence technologies on the Biograph family of positron emission tomography/computed tomography (PET/CT) systems
News | Artificial Intelligence
FDA Clears Siemens AIDAN Artificial Intelligence for Biograph PET/CT Portfolio

April 22, 2020 — Siemens Healthineers has received clearance from the Food and Drug Administration (FDA) for its AIDAN ...

Time April 22, 2020
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Maximum-intensity PET projections at each time point for one rhesus monkey in the 89Zr-DFO-squaramide-anti-gD group.
News | PET Imaging
Total-body PET Imaging Successfully Identifies Antibodies up to 30 Days After Injection

April 10, 2020 — Combining 89Zr-labeled antibodies with total-body positron emission tomography (PET) has extended the ...

Time April 10, 2020
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RefleXion Medical, a therapeutic oncology company pioneering the use of biology-guided radiotherapy (BgRT) to treat all stages of cancer, announced the first sale of its RefleXion X1 machine to the Stanford Cancer Institute.
News | PET Imaging
RefleXion Announces First Sale of X1 Machine for Cancer Treatment

April 9, 2020 — RefleXion Medical, a therapeutic oncology company pioneering the use of biology-guided radiotherapy ...

Time April 09, 2020
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Videos | Coronavirus (COVID-19)
VIDEO: Best Practices for Nuclear Cardiology During the COVID-19 Pandemic

Hicham Skali, M.D., a staff cardiologist and member of the Non-invasive Cardiovascular Imaging Program at Brigham and ...

Time April 04, 2020
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Recommended best practices for nuclear imaging departments under the COVIF-19 pandemic have been issues by the ASNC and SNMMI. #COVID19 #ASNC #SNMMI #Coronavirus #SARScov2
News | Coronavirus (COVID-19)
Best Practices for Nuclear Imaging During the Coronavirus (COVID-19) Pandemic

April 3, 2020 — A new guidance document on best practices to maintain safety and minimize contamination in nuclear ...

Time April 03, 2020
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Novel scanners may open door for prognostic assessment in patients receiving cochlear implants
News | PET-CT
High-resolution PET/CT Assesses Brain Stem Function in Patients with Hearing Impairment

March 26, 2020 — Novel, fully digital, high-resolution positron emission tomography/computed tomography (PET/CT) imaging ...

Time March 26, 2020
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PSMA PET-CT is a suitable replacement for conventional imaging, providing superior accuracy, to the combined findings of CT and bone scanning
News | Prostate Cancer
Prostate Cancer Study Finds Molecular Imaging Could Transform Management of Patients with Aggressive Cancer

March 23, 2020 — Results from a randomised controlled trial involving 300 prostate cancer patients find that a molecular ...

Time March 23, 2020
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