News | Radiopharmaceuticals and Tracers | February 16, 2017

Cerveau Technologies Signs Manufacturing Agreement with Siemens’ PETNET Solutions for Investigational Tau Imaging Agent

MK-6240 doses for Alzheimer’s-related clinical trial to be manufactured and supplied by PETNET Solutions’ locations in the U.S.

February 16, 2017 — Cerveau Technologies Inc. announced it has signed an agreement with Siemens’ PETNET Solutions Inc. that grants the company the right to manufacture [F-18]MK-6240, an early-stage investigational poistron emission tomography (PET) imaging agent. [F-18]MK-6240 is currently being evaluated to image neurofibrillary tangles (NFTs) in the brain. NFTs made up of aggregated tau protein are a hallmark of several neurodegenerative diseases, including Alzheimer’s disease.

Under the terms of its agreement with Cerveau, Siemens’ PETNET Solutions Inc. will initially manufacture [F-18]MK-6240 clinical trial material at select U.S. radiopharmacies, with the possibility of expanding into additional locations.

Siemens’ PETNET Solutions Inc. operates a large network of PET radiopharmaceutical drug manufacturing facilities and dispensing nuclear pharmacies, with over 50 locations worldwide. The company manufactures and dispenses PET radiopharmaceuticals for hospitals, clinics and research facilities worldwide.

For more information:  www.usa.healthcare.siemens.com

Related Content

Technology | Pediatric Imaging | July 21, 2017
The U.S. Food and Drug Administration (FDA) has cleared the first magnetic resonance imaging (MRI) device specifically...
PET/CT Tracer Identifies Vulnerable Lesions in Non-Small Cell Lung Cancer Patients

Example of a patient with an upper left lung NSCLC: A: FDG; B: FDG PET/CT; C: Planning radiotherapy based on FDG (66Gy) with BTVm (GTV), CTV and PTV; D: PET FMISO E: FMISO PET/CT; F: boost based on the FMISO PET (76Gy) with BTVh (biological hypoxic target volume) and PTV boost. Credit: QuantIF – LITIS EA 4108 – FR CNRS 3638, Henri Becquerel Cancer Center, Rouen, France

News | PET-CT | July 14, 2017
July 14, 2017 — Fluorine-18 (18F)-fluoromisonidazole (FMISO) is a positron emission tomography (PET)...
Researchers Identify Visual System Changes that May Signal Parkinson's Disease
News | Neuro Imaging | July 11, 2017
Changes in the visual systems of newly diagnosed Parkinson’s disease patients may provide important biomarkers for the...
Novel PET Tracer Detects Small Blood Clots

PET images (MIP 0-60 min) of three Cynomolgus monkeys. Strong signals are detected at the sites where inserted catheters had roughened surfaces. Almost no other background signal is visible. Only accumulation in the gallbladder becomes visible at the bottom of the image. Credit: Piramal Imaging GmbH, Berlin Germany.

News | PET Imaging | July 07, 2017
July 7, 2017 — Blood clots in veins a
New Study Uses MRI to Probe Psychopathic Brains
News | Neuro Imaging | July 07, 2017
Josh Buckholtz, Ph.D., associate professor of psychology at Harvard University, is the senior author of a study that...
American Society of Neuroradiology Launches Anne G. Osborn International Outreach Professor Program
News | Neuro Imaging | July 05, 2017
The American Society of Neuroradiology (ASNR) recently announced the creation of the Anne G. Osborn ASNR International...
Sponsored Content | Videos | Clinical Decision Support | June 29, 2017
Rami Doukky, M.D., system chair, Division of Cardiology, professor of medicine, Cook County Health and Hospitals Syst
Dual-Agent PET/MR With Time of Flight Detects More Cancer

Tc-99m MDP bone scan (left) is negative for osseous lesions. NaF/FDG PET/MRI (right and second slide) confirms absence of bone metastases, but shows liver metastases. Image courtesy of Stanford University.

News | PET-MRI | June 20, 2017
Simultaneous injections of the radiopharmaceuticals fluorine-18 fluorodeoxyglucose (18F-FDG) and 18F-sodium fluoride (...
Combined Optical and Molecular Imaging Could Guide Breast-Conserving Surgery

WLE specimen from a patient with a grade 3, ER-/HER2-, no special type (NST) carcinoma. (A) Cerenkov image; (B) Grey-scale photographic image overlaid with Cerenkov signal. An increased signal from the tumor is visible (white arrows); mean radiance is 871 ± 131 photons/s/cm2/sr, mean TBR is 3.22. Both surgeons measured the posterior margin (outlined in blue) as 2 mm (small arrow); a cavity shaving would have been performed if the image had been available intraoperatively. The medial margin (outlined in green) measured >5 mm by both surgeons. Pathology ink prevented assessing the lateral margin; a phosphorescent signal is visible (open arrows). (C) Specimen radiography image. The absence of one surgical clip to mark the anterior margin, and the odd position of the superior margin clip (white arrow) prevented reliable margin assessment. (D) Combined histopathology image from two adjacent pathology slides on which the posterior margin (bottom of image) and part of the primary tumor are visible (open arrows). The distance from the posterior margin measured 3 mm microscopically (double arrow). The medial margin is > 5 mm (not present in image). Credit: A. D. Purushotham, M.D., King’s College London, UK

News | Nuclear Imaging | June 20, 2017
June 20, 2017 — Breast-conserving surgery (BCS) is the primary treatment for early-stage...
A 77-year-old male with recurrent lymph node and pulmonary metastases detected by Ga-68 PSMA PET/CT but not by conventional imaging

A 77-year-old male with recurrent lymph node and pulmonary metastases detected by Ga-68 PSMA PET/CT but not by conventional imaging. Graphic courtesy of the Department of Nuclear Medicine, Royal North Shore Hospital, Sydney

News | Prostate Cancer | June 15, 2017
An estimated one in seven American men will be affected by prostate cancer in their lifetime. Prostate-specific...
Overlay Init