News | Radiation Therapy | September 12, 2019

RefleXion Highlights Novel Approach to Radiotherapy at ASTRO 2019

Biology-guided radiotherapy may improve treatment for early-stage cancer and expand options for metastatic disease

RefleXion Highlights Novel Approach to Radiotherapy at ASTRO 2019

The RefleXion X1 Machine without the Gantry Cover. The patented technology incorporates PET imaging data, which enables tumors to continuously signal their location. Image courtesy of Reflexion Medical.

September 12, 2019 – Therapeutic oncology company RefleXion Medical announced it will showcase the RefleXion X1 Machine at the American Society for Radiation Oncology (ASTRO) 2019 annual meeting, Sept. 15-18 in Chicago. The company says its biology-guided radiotherapy (BgRT) platform is the first and only technology that unlocks the biological signature of each tumor to characterize its movement and direct highly conformal treatment to the tumor.

RefleXion also announced it will host a series of events with industry thought leaders highlighting combination therapies for metastatic disease. 

“Evidence is weak for clinically relevant systemic effects of single-lesion radiation in metastatic cancer, however recent studies suggest that immunotherapy may augment the local effects of radiotherapy,” said Jason Luke, M.D., director of the Cancer Immunotherapeutics Center at UPMC Hillman Cancer Center and associate professor of medicine at the University of Pittsburgh School of Medicine. 

“Prior studies have used conventional stereotactic radiotherapy approaches generally treating one or two tumors,” continued Luke. “The potential for BgRT to treat more sites of disease may facilitate a massive reduction in tumor burden and potentially augment systemic immune activation. For the oncology community, exploring the combination of BgRT with cancer immunotherapy is of high interest to improve outcomes for patients.”

RefleXion’s approach offers a significant change in strategy from single-tumor therapy to the ability to one day treat multiple targets in the same treatment session in cancers that have metastasized. The technology incorporates a well-established modality for cancer staging and imaging, positron emission tomography (PET), which enables tumors to continuously signal their location. Using the anatomic data from computed tomography (CT) and the PET imaging data, the RefleXion machine detects PET emissions and immediately sends beamlets of radiation directly to the tumor to destroy it. The RefleXion machine also improves upon the delivery of conventional radiotherapy for single-site cancers.

The RefleXion Machine requires U.S. Food and Drug Administration (FDA) 510(k) clearance and is not yet commercially available in the United States.

For more information: www.reflexion.com

Related Content

Videos | Radiation Oncology | October 11, 2019
Lorraine Drapek, DNP, nurse practitioner, radiation oncology, GI service,...
Patient Treatments With ViewRay's MRIdian Linac Begin in New England
News | Image Guided Radiation Therapy (IGRT) | October 08, 2019
ViewRay Inc. announced today that patient treatments are scheduled to begin in Boston with ViewRay's MRIdian Linac...
ProTom International received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Radiance 330 proton therapy system
News | Proton Therapy | October 07, 2019
ProTom International received 510(k) clearance from the U.S.
Attendees of ASTRO 2019 walked the halls of McCormick Place in Chicago, Ill.

Attendees of ASTRO 2019 walked the halls of McCormick Place in Chicago, Ill.

Feature | ASTRO | October 03, 2019 | By Greg Freiherr
At the American Society for Radiation Oncology’s (ASTRO) 2019 a
Videos | Prostate Cancer | September 30, 2019
Bill Hartsell, M.D., medical director of the Northwestern Medicine Proton Center in Warrenville, Ill., discusses the
eBook on Hypofractionation in the Age of Value-based Care

eBook on Hypofractionation in the Age of Value-based Care

Sponsored Content | Case Study | Radiation Therapy | September 30, 2019
Hypofractionated and ultrahypofractionated radiation therapy — increasing dose per fraction to enable significantly f
AI Accurately Predicts Radiotherapy Side Effects for Head and Neck Cancer Patients
News | Artificial Intelligence | September 26, 2019
For the first time, a sophisticated computer model has been shown to accurately predict two of the most challenging...