News | Radiation Therapy | April 29, 2019

Novel Software Improves Accuracy of Radiation Therapy for Pediatric Cancer Treatment

Study examines use of Sun Nuclear’s PerFraction software to automate adjustment of treatment planning

Novel Software Improves Accuracy of Radiation Therapy for Pediatric Cancer Treatment

April 29, 2019 — A new report by Arthur Olch, Ph.D., highlights use of specialized software at Children’s Hospital Los Angeles (CHLA) that could advance treatment accuracy of radiation oncology for pediatric cancer patients.

During radiation therapy, patient position must be stable from session to session to ensure radiation beams are properly targeting the tumor. For this reason, X-ray images are taken before each treatment. Radiation therapists can use this information to reorient the patient so that the position is exactly the same each time. Doctors at CHLA are taking this already rigorous process one step further. From early in its development Olch, a radiation physicist, has been evaluating the use of new software to advance quality assurance in radiation therapy. In a recent publication, he highlights the use of this technological advance to aid in the treatment of pediatric cancers.

Radiation therapy uses a beam of targeted X-rays that kill cancer cells over the course of treatment. After the beam passes through the patient, it is captured on an imaging panel. Olch and his team make use of the information carried by these beams, called exit images, using the automated software. These images contain important information about the exact dose being delivered to the tumor and surrounding tissues and can be compared to the planned doses. Up to 20 images might be generated per treatment session. With treatments occurring every day for several weeks, this makes for an unwieldy amount of data to manually process. Now, radiation oncology staff have a tool that will do this in seconds. The program automates not only image capture but also analysis.

Analyzing these images provides new information that allows further fine tuning of the radiation beams and patient position from session to session. This, said Olch, gives radiation oncologists more information that can be used to account for anatomy changes in real time. "If a patient gains or loses weight, their dimensions change" he said. "Likewise, as the tumor shrinks, radiation beams need to take a different trajectory."

Adjustments are routinely made as a standard of care, but by utilizing the latest technological advances, CHLA radiation oncologists are redefining this standard. "We have a very comprehensive quality assurance strategy," said Olch, "and this software is an important addition to our already high standard of care."

Olch is also a professor of clinical radiation oncology at the University of Southern California (USC). He co-authored the publication with Kyle O'Meara and Kenneth Wong, M.D. Olch provides consulting services to Sun Nuclear Corp., who provided PerFraction software but did not fund the study.

For more information: www.advancesradonc.org

Reference

1. Olch A.J., O’Meara K., Wong K. First Report of the Clinical use of a Commercial Automated System for Daily Patient QA using EPID Exit Images. Advances in Radiation Oncology, published online April 12, 2019. https://doi.org/10.1016/j.adro.2019.04.001

Related Content

LVivo EF Comparable to MRI, Contrast Echo in Assessing Ejection Fraction
News | Cardiovascular Ultrasound | June 19, 2019
DiA Imaging Analysis announced the presentation of two studies assessing the performance and accuracy of the company's...
New Data Demonstrates Safety Profile of GammaTile Therapy for Various Brain Tumors
News | Brachytherapy Systems | June 18, 2019
GT Medical Technologies Inc. announced the presentation of clinical data from a prospective study of GammaTile Therapy...
Black Men Less Likely to Adopt Active Surveillance for Low-Risk Prostate Cancer
News | Prostate Cancer | June 17, 2019
A new study reveals black men are less likely than white men to adopt an active surveillance strategy for their...
University Medical Center Groningen Performs First Automatic Log-based Proton Therapy Patient QA
News | Proton Therapy | June 14, 2019
IBA announced the physics team of University Medical Center Groningen (UMCG) in the Netherlands has developed and...
ASTRO Applauds New Prior Authorization Legislation
News | Radiation Therapy | June 07, 2019
The American Society for Radiation Oncology (ASTRO) released a statement applauding Congress’s introduction of...
IBA Dosimetry Launches myQA iON
News | Quality Assurance (QA) | June 07, 2019
IBA (Ion Beam Applications S.A.) announced the launch of myQA iON at the 2019 Particle Therapy Co-Operative Group (...
Study Identifies MRI-Guided Radiation Therapy as Growing Market Segment
News | Image Guided Radiation Therapy (IGRT) | June 06, 2019
Revenues from the magnetic resonance imaging (MRI)-guided radiation therapy systems market exceeded $220 million in...
Ann Arbor Startup Launches Augmented Reality MRI Simulator
Technology | Virtual and Augmented Reality | June 04, 2019
SpellBound, an Ann Arbor startup specializing in augmented reality (AR) tools for children in hospitals, has officially...
RefleXion Opens New Manufacturing Facility for Biology-guided Radiotherapy Platform
News | Radiation Therapy | May 31, 2019
RefleXion Medical recently announced the opening of its new manufacturing facility at its headquarters in Hayward,...
AI Biomarker Demonstrates High Predictive Power for Lung Cancer Immunotherapy
News | Artificial Intelligence | May 31, 2019
Lunit announced an abstract presentation of its artificial intelligence (AI) precision medicine research portfolio at...