News | Magnetic Resonance Imaging (MRI) | February 19, 2019

MRI and Computer Modeling Reveals How Wrist Bones Move

Advanced 3-D MRI technique proves that right and left wrists mirror each other, but that male and female wrists are different

MRI and Computer Modeling Reveals How Wrist Bones Move

Using fast MRI, UC Davis researchers scanned left and right wrists of men and women and used the data to build computer models of the movement of wrist bones. The data could help understand wrist injuries such as carpal tunnel syndrome. Image courtesy of Brent Foster and Abhijit Chaudhari, UC Davis.

February 19, 2019 — In a just-published Journal of Biomechanics article1, the researchers proved a longtime assumption about individuals' right and left wrists, while also finding differences between wrists of males and females. These discoveries could help inform and guide future treatments.

"If someone has dysfunction of the wrist, it really impacts their quality of life," said UC Davis Biomedical Engineering Graduate Group member and article first author Brent Foster, who also was selected for a prestigious National Science Foundation Graduate Research Fellowship to create a wrist-anatomy model. Foster currently is a graduate student in the lab of Abhijit Chaudhari, Ph.D., in the UC Davis Department of Radiology, and his co-authors include orthopedic surgeons, a radiologist and medical imaging experts at UC Davis and the University of Southern California.

Foster and his team scanned both wrists of 18 individuals — nine men and nine women of varying ages — with no history of wrist injuries, disease or pain. Using innovative magnetic resonance imaging (MRI) techniques that allow 3-D views of wrists in motion, the researchers had individuals move their wrists in five ways while being scanned to track the movement of the wrist bones and joint. They then used advanced mathematical techniques to analyze the images to generate robust models of wrist motion.

"While each wrist bone had been studied individually before, our work really focuses on how wrist bones move and act together," Foster said.

The results showed that while individual's left and right wrists are similar, there were gender-based wrist differences. While wrist-based therapies had assumed that individuals' left and right wrists mirrored each other, there has been insufficient evidence to back this assumption up until now.

The researchers initially hypothesized that there would not be significant wrist differences found between the male and female volunteers. But their measurements changed their minds: "While there is literature about scaling differences between male and female wrists, we are able to examine if bone trajectories during wrist motion differ by gender," said Foster.

Wrist conditions such as carpal tunnel syndrome do disproportionately affect women, although it's not clear why, Chaudhari said.

"There have historically been several theories about what wrist bones do during motion, and some cadaveric studies to support them. Analysis performed based on some of these theories illustrates sex differences, but that based on others doesn't," he said. The new fast MRI and computed tomography (CT) scanning techniques allow researchers to study live wrist bones in motion for the first time.

Foster, Chaudhari and colleagues look forward to continuing their efforts to help people experiencing wrist pain and disorders like osteoarthritis and carpal-tunnel syndrome.

"By scanning just five basic wrist movements, we were able to explain over 91 percent of wrist variation across individuals," he said. "We're excited to use these innovative MRI and analysis methods to make a difference in managing wrist disorders."

For more information: www.journals.elsevier.com/journal-of-biomechanics

Reference

1. Foster B.H., Shaw C.B., Boutin R.D., et al. A principal component analysis-based framework for statistical modeling of bone displacement during wrist maneuvers. Journal of Biomechanics, Jan. 24, 2019. https://doi.org/10.1016/j.jbiomech.2019.01.030

Related Content

3D Systems Earns Additional FDA Clearance for D2P Medical 3-D Printing Software

3D Systems’ D2P FDA-cleared software allows clinicians to 3-D-print diagnostic patient-specific anatomic models. Image courtesy of 3D Systems.

Technology | Medical 3-D Printing | September 12, 2019
3D Systems has received additional U.S. Food and Drug Administration (FDA) 510(k) clearance for its D2P software...
Imaging Biometrics and Medical College of Wisconsin Awarded NIH Grant
News | Neuro Imaging | September 09, 2019
Imaging Biometrics LLC (IB), in collaboration with the Medical College of Wisconsin (MCW), has received a $2.75 million...
ASNC Announces Multisocietal Cardiac Amyloidosis Imaging Consensus
News | Cardiac Imaging | September 09, 2019
September 9, 2019 — The American Society of Nuclear Cardiology (ASNC) published a new expert consensus document along
AJR Publishes Gender Affirmation Surgery Primer for Radiologists. transgender radiology images,

Scout image from contrast-enhanced CT shows erectile implant; stainless steel and silicone anchors (arrow) transfixed to pubic bone are asymmetric.

News | Orthopedic Imaging | September 05, 2019
September 5, 2019 — An ahead-of-print article published in the December issue of the American Journal of Roentgen
Neurological Brain Markers Might Detect Risk for Psychotic Disorders

Researchers at the University of Missouri used MRI scans similar to this photo to find neurological markers in the human brain. These markers can be used to detect people at risk for developing psychotic disorders and to understand when this risk has been successfully treated. Image courtesy of Marquette University/John Kerns.

News | Neuro Imaging | September 04, 2019
Help may be on the way for people who might lose contact with reality through a psychotic disorder, such as...
Medical Imaging Rates Continue to Rise Despite Push to Reduce Their Use
News | Radiology Imaging | September 03, 2019
Despite a broad campaign among physician groups to reduce the amount of medical imaging, use rates of various scans...
High-capacity MRI Scanner Approvals Boosting Innovations in MRI-safe Pulse Oximeters
News | Magnetic Resonance Imaging (MRI) | August 29, 2019
A notable increase in the prevalence of chronic diseases has led to a surge in sales of high-end diagnostic machines,...
Delaware Imaging Network Now Offers NeuroQuant Brain Imaging MRI Software
News | Neuro Imaging | August 29, 2019
Delaware Imaging Network (DIN), Delaware’s largest network of outpatient medical imaging centers, has added NeuroQuant...
Displacement comparison at the end-systolic frame and final frame

Displacement comparison at the end-systolic frame and final frame. The three patients (V6, V10, V16) with different left-ventricle walls are shown. Point-to-surface distance is a measure to estimate the distance of a point from the reference surface. Image courtesy of WMG, University of Warwick

News | Cardiac Imaging | August 28, 2019
A new 3-D magnetic resonance imaging (MRI) computing technique developed by scientists in WMG at the University of...
Smoldering Spots in the Brain May Signal Severe MS

NIH researchers found that dark rimmed spots representing ongoing, “smoldering” inflammation, may be a hallmark of more disabling forms of multiple sclerosis. Image courtesy of Reich lab, NIH/NINDS.

News | Neuro Imaging | August 22, 2019
Aided by a high-powered brain scanner and a 3-D printer, National Institutes of Health (NIH) researchers peered inside...