News | Proton Therapy | April 25, 2019

California Protons Cancer Therapy Center Begins Breast Cancer Study Enrollment

Patients invited to participate in Proton Collaborative Group (PCG) Registry and clinical trial of partial breast irradiation in early-stage breast cancer

California Protons Cancer Therapy Center Begins Breast Cancer Study Enrollment

April 25, 2019 — California Protons Cancer Therapy Center announced two major efforts representing significant steps forward in breast cancer treatment research involving its noninvasive, targeted proton therapy. Current California Protons patients as of Feb. 4, 2019, are invited to enroll in the Proton Collaborative Group (PCG) Registry of more than 13,000 patients. Separately, the PCG BRE007-12 Partial Breast Irradiation in early-stage breast cancer clinical trial will enroll around five to eight females per year.

The PCG Registry has been in existence since 2010. It is a prospective tracking study that allows for the collection and analysis of patient information to evaluate the disease process and treatment-related outcomes, thus defining strengths and weaknesses of proton radiation therapy. Qualified patients are invited to enroll in person at their first physician visit during treatment.

The primary objective of the PCG BRE007-12 Partial Breast Irradiation study is to determine freedom from ipsilateral breast recurrences in patients receiving partial breast proton radiation therapy limited to the region of the tumor at three years post-treatment. One of the goals of this study is to determine whether or not limiting radiation to just a portion of the breast is as effective as the traditional treatment of the entire breast. A number of trials have suggested that this “partial breast” approach is every bit as effective as treating the entire breast and may also be less toxic. Performing such partial breast treatments with protons can help to further reduce toxicity by taking advantage of the protons’ ability to be precisely conformed to the target area without giving “spillover” radiation to surrounding healthy tissue such as the lung and heart.

PCG has partnered with 11 proton treatment centers in the U.S., and the data has been used in close to 50 scientific manuscripts, posters and academic presentations to date. PCG research has been presented at 20 medical conferences and has been published in a number of peer-reviewed medical journals.

Both the Patient Registry and the Partial Breast Irradiation Trial are Institutional Review Board (IRB)-approved. These breast cancer trials supplement California Protons Cancer Therapy Center’s ongoing research projects with the University of California San Diego (UCSD) and the Radiation Therapy Oncology Group (RTOG) Foundation 3510 Phase III randomized trial of proton versus photon therapy for patients with nonmetastatic breast cancer receiving comprehensive nodal radiation.

Watch the VIDEO: Whole Versus Partial Radiotherapy for Breast Cancer

For more information: www.californiaprotons.com

Related Content

High-dose Radiation Effective for Men Whose Prostate Cancer Has Spread
News | Prostate Cancer | September 23, 2019
A randomized clinical trial of targeted, high-dose radiation for men with oligometastatic prostate cancer has shown the...
First Patients Treated With Machine Learning-generated Plans from RayStation 8B
News | Treatment Planning | September 23, 2019
The first-ever patient radiation therapy treatments generated with machine learning in the RayStation treatment...
An example of a treatment plan for radio-ablation of the heart to noninvasively treat cardiac arrhythmias. This concept is one of the key presentations at the 2019 ASTRO meeting. Image courtesy of Cyberheart. #ASTRO19 #ASTRO2019 #ASTRO

An example of a treatment plan for radio-ablation of the heart to noninvasively treat cardiac arrhythmias. This concept is one of the key presentations at the 2019 ASTRO meeting. Image courtesy of Cyberheart.

Feature | ASTRO | September 23, 2019
August 29, 2019 — The American Society for Radiation Oncology (ASTRO) announced th
Videos | Radiation Oncology | September 20, 2019
Anne Hubbard, MBA, director of health policy for ASTRO, explains the details and purpose of the proposed Radiation On
Densitas Wins Major Procurement of Breast Density Software for DIMASOS Breast Screening Trial
News | Breast Density | September 20, 2019
Densitas Inc. announced it has won a procurement of its densitas densityai software for deployment in up to 24 breast...
Numerical simulation with a heterogeneous mouse

Numerical simulation with a heterogeneous mouse. (a) The geometry of the mouse with major organs near the source, and (b) the surface fluence computed with TIM-OS. Image courtesy of Rensselaer Polytechnic Institute.

News | Oncology Diagnostics | September 20, 2019
If researchers could observe drug delivery and its effect on cancer cells in real time, they would be able to tailor...
Videos | Radiation Therapy | September 20, 2019
ITN Associate Editor Jeff Zagoudis speaks with...
Aktina Showcases New Radiotherapy Patient Immobilization Solutions at ASTRO 2019
News | Patient Positioning Radiation Therapy | September 20, 2019
Aktina Medical introduced several new products at the 2019 American Society for Radiation Oncology (ASTRO) annual...
Varian Announces Multi-room Configuration for ProBeam 360 Proton Therapy System
News | Proton Therapy | September 20, 2019
Varian announced its ProBeam 360° proton therapy system is now available in a multi-room configuration. The ProBeam 360...
Screening Mammography Could Benefit Men at High Risk of Breast Cancer
News | Mammography | September 18, 2019
Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at...